Results 81 to 90 of about 2,422,535 (304)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Benchmarking for a New Railway Accident Classification Methodology and Its Database: A Case Study in Mexico, the United States, Canada, and the European Union

Information
Rail accidents have decreased in recent years, although not significantly if measured by train accidents recorded in the last six years. Therefore, it is essential to identify weaknesses in the implementation of security and prevention systems.
Tania Elizabeth Sandoval-Valencia, Adriana del Carmen Téllez-Anguiano, Dante Ruiz-Robles, Ivon Alanis-Fuerte, Alexis Vaed Vázquez-Esquivel, Juan C. Jáuregui-Correa   +5 more
doaj   +1 more source

Analysis of women participation in cassava production and processing in Imo state, southeast Nigeria

Agricultura Tropica et Subtropica, 2012
The study examined the participation of women in cassava production and processing in Imo State, Nigeria. Stratifi ed and simple random samplings were used to select 60 women that engage in the enterprise in the state.
Onyemauwa C.S.
doaj   +1 more source

Measuring reproducibility of high-throughput experiments

, 2011
Reproducibility is essential to reliable scientific discovery in high-throughput experiments. In this work we propose a unified approach to measure the reproducibility of findings identified from replicate experiments and identify putative discoveries ...
Bickel, Peter J., Brown, James B., Huang, Haiyan, Li, Qunhua   +3 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Statistics for Human Biologist - Introduction

Human Biology and Public Health
For many researchers in the field of human biology, statistics is a foreign territory where they feel uncomfortable because of statistical vocabulary used and the many different ways of analyzing their data.
Detlef Groth
doaj  

Descriptive Statistics and Genome-Wide Copy Number Analysis of Milk Production Traits of Jiangsu Chinese Holstein Cows. [PDF]

Animals (Basel), 2023
Zhu H, Lu X, Jiang H, Yang Z, Xu T.
europepmc   +1 more source

IMPROVING STUDENTS’ WRITING SKILL USING A FOUR-PHASE TECHNIQUE [PDF]

, 2012
This article describes a classroom action research held in writing class using a four-phase technique to improve the eleventh grade students’ writing skill and improve classroom situation.
Rais, A. Dahlan, Utami, Fitria Siti
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Descriptive statistics and risk factor analysis of children with community-acquired septic shock. [PDF]

J Intensive Care, 2023
Miura S, Michihata N, Hashimoto Y, Matsui H, Fushimi K, Yasunaga H.   +5 more
europepmc   +1 more source