Results 111 to 120 of about 560,036 (321)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Quality Assessment of Young Sparkling Wines of Crimean Indigenous Grape Varieties
Техника и технология пищевых производствMost domestic sparkling wines are made of traditional champagne grape varieties. However, indigenous Crimean cultivars could increase the output of high-quality original beverages if a proper technology was introduced.
Igor P. Lutkov +2 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Applied SciencesComputational approaches applied in drug discovery have advanced significantly over the past few decades. These techniques are commonly grouped under the term “computer-aided drug design” (CADD) and are now considered one of the key pillars of ...
Boris Vasilev, Mariyana Atanasova
doaj +1 more source
ROAM: Robust and Object-Aware Motion Generation Using Neural Pose Descriptors [PDF]
, 2023 Wanyue Zhang +5 more
openalex +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Model-based plant phenomics on morphological traits using morphometric descriptors
, 2022 Koji Noshita +2 more
openalex +2 more sources
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Revue Archéologique du Centre de la FranceThis work deals with the organization of the countryside to the northwest of the agglomeration of Orléans (Loiret) during the Roman period, from 1st century BC to the 5th century AD It is based on data from documentation about rural settlements surveyed,
Laure de Souris
doaj
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source