Results 151 to 160 of about 405,178 (360)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Permeability and Porosity Estimation Using Textural Descriptors

open access: yes, 2020
Porosity and permeability are critical petrophysical properties for reservoir modelling as they represent the reservoir's ability to store and transmit fluids.
Archer, Rosalind, Prieto, Angela
core  

Quality Assessment of Young Sparkling Wines of Crimean Indigenous Grape Varieties

open access: yesТехника и технология пищевых производств
Most domestic sparkling wines are made of traditional champagne grape varieties. However, indigenous Crimean cultivars could increase the output of high-quality original beverages if a proper technology was introduced.
Igor P. Lutkov   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A (Comprehensive) Review of the Application of Quantitative Structure–Activity Relationship (QSAR) in the Prediction of New Compounds with Anti-Breast Cancer Activity

open access: yesApplied Sciences
Computational approaches applied in drug discovery have advanced significantly over the past few decades. These techniques are commonly grouped under the term “computer-aided drug design” (CADD) and are now considered one of the key pillars of ...
Boris Vasilev, Mariyana Atanasova
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

gCube parameter descriptors

open access: yes, 2018
TDM Operation module defining parametrs types. <br> <br><strong>Documentation</strong> <br> Documentation is available on-line in the gCube Wiki:<br> <a href="https://wiki.gcube-system.org/gcube/index.php ...
Fabio Sinibaldi (5203090)   +3 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Descriptors of water aggregation

open access: yesThe Journal of Chemical Physics
We rely on a total of 23 (cluster size, 8 structural, and 14 connectivity) descriptors to investigate structural patterns and connectivity motifs associated with water cluster aggregation. In addition to the cluster size n (number of molecules), the 8 structural descriptors can be further categorized into (i) one-body (intramolecular): covalent OH bond
Garrett D. Santis   +3 more
openaire   +2 more sources

Organisation et dynamiques de l’occupation du sol au nord-ouest de Cenabum-Orléans (Loiret) du ier s. av. n. è. au ve s. de n. è.

open access: yesRevue Archéologique du Centre de la France
This work deals with the organization of the countryside to the northwest of the agglomeration of Orléans (Loiret) during the Roman period, from 1st century BC to the 5th century AD It is based on data from documentation about rural settlements surveyed,
Laure de Souris
doaj  

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