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Successful desensitization and early outcomes in two highly sensitized living-related kidney transplant recipients at IBN Sina Teaching Hospital, Sirte, Libya

World Journal of Advanced Research and Reviews
Highly sensitized kidney transplant candidates face significant immunologic barriers due to high donor-specific antibody (DSA) titers. This study reports the first two highly sensitized living-related kidney transplant recipients successfully ...
Mohamed Aboalgasem   +7 more
semanticscholar   +1 more source

Immunological aspects of oral desensitization in food allergy.

Digestive diseases and sciences, 2000
IMMUNOLOGY ASPECTS OF ORAL DESENSITIZATION IN FOOD ...
Nucera, Eleonora   +6 more
openaire   +4 more sources

Long-term IgE immunological tolerance to peanut allergens: An alternative to Noon’s daily desensitization paradigm

Cellular Immunology, 2022
Herein, we show that profound afferent long-term peanut-allergen-specific IgE immunological tolerance for 3 to 9 months induced sustained unresponsiveness (SU) in naïve or peanut-sensitized rodents after peanut allergen immunization. Rodents were vaccinated sublingually with a peanut allergen extract or recombinant peanut allergen in chenodeoxycholate (
Swey-Shen Chen   +4 more
openaire   +2 more sources

Insulin allergy. Clinical and immunological effects of specific desensitization

Acta Diabetologica Latina, 1969
Five patients with insulin allergy were desensitized with porcine insulin according to the method of Urbach and Gotlieb. The diagnosis of insulin allergy was based on clinical manifestations, positive skin tests, and, moreover, on positive Prausnitz-Kustner (P.K.) reactions in 2 cases. Successful desensitization was obtained in 3 cases.
openaire   +2 more sources

Penicillin desensitization: correlation of clinical and immunological events using an in vitro model

Clinical & Experimental Allergy, 1972
SummaryA patient with actinomycosis was found to have immediate hypersensitivity to penicillin by previously described skin testing methods as well as by a recently described in vitro system utilizing rat peritoneal mast cells. Desensitization to penicillin became imperative, but in using the classical route (the intracutaneous route), systemic ...
S A, Gillman, J L, Korotzer, Z H, Haddad
openaire   +2 more sources

Immunologic parameters and viral infections in patients desensitized with intravenous immunoglobulin and rituximab

Transplant Immunology, 2011
Desensitization with IVIG and rituximab followed by transplantation with alemtuzumab or daclizumab induction is an effective clinical protocol. Here, we examined the effects of this protocol on immune cell number, T cell function by Cylex ImmuKnow®, CMV-specific CD8+ T cell (CMV-Tc) activity, total and viral-specific immunoglobulin levels and viral ...
Shili, Ge   +12 more
openaire   +2 more sources

Aspirin desensitization for patients with aspirin-exacerbated respiratory disease: A randomized double-blind placebo-controlled trial.

Clinical Immunology, 2015
The effect of aspirin desensitization (AD) on immunologic profile of patients with AERD has been poorly understood. This study is aimed at investigating the effect of AD on clinical and immunological markers of patients with AERD.
H. Esmaeilzadeh   +6 more
semanticscholar   +1 more source

Patient and Graft Outcome Among High Immunologic Risk Renal Transplant Recipients

Transplantation, 2018
Introduction Kidney transplantation (KT) is the preferred treatment for ESRD. However, some patients had prior HLA sensitization making them immunologically high risk for graft rejection and poorer graft survival.
J. Mora   +3 more
semanticscholar   +1 more source

Immunologic Changes in Frail Older Adults

Translational medicine @ UniSa, 2014
Several studies have shown a heightened inflammatory state in frail older adults, marked by high serum levels of interleukin-6 and C-reactive protein and an increased number of circulating leukocytes.
G. Wang, V. Casolaro
semanticscholar   +1 more source

[New immunologic perspectives on specific desensitization].

Schweizerische medizinische Wochenschrift, 1978
The development of objective techniques for the quantitative evaluation of synthesis and production of IgE in man and experimental animals and the sensitivity of basophils in interaction with allergen has made it possible to initiate studies on desensitization on a scientific and objective basis.
openaire   +1 more source

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