Results 261 to 270 of about 158,350 (323)

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β‐arrestin recruitment and the discovery of an allosteric agonist

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lactate, historically viewed as a metabolic by‐product, has emerged as a signalling molecule via the G protein–coupled receptor Hydroxycarboxylic Acid Receptor 1 (HCAR1). The receptor is primarily expressed in adipocytes but also found in various other tissues.
Simon Lind   +6 more
wiley   +1 more source

Comparison of dentinal hydraulic conductance according to the application time of oxalate-based desensitizers

open access: green, 2015
Maria Aparecida Rodrigues. ROMERO   +6 more
openalex   +1 more source

β3‐adrenoceptor agonism exerts lung protection in a rat model of bronchopulmonary dysplasia

open access: yesBritish Journal of Pharmacology, EarlyView.
The β3‐adrenoceptors agonist BRL37344 promotes lung maturation, preventing the progression of experimental bronchopulmonary dysplasia. Absract Background and Purpose Bronchopulmonary dysplasia (BPD) affects premature newborns, particularly those receiving supplemental oxygen therapy.
Alessandro Pini   +14 more
wiley   +1 more source

Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N‐ERD Patients

open access: yesClinical &Experimental Allergy, EarlyView.
Dupilumab therapy reduced elevated type 2 cytokine responses post‐ASA provocation in N‐ERD patients, independent of ASA tolerance, and revealed novel mechanistic insights by modulating acute type 2 immunity. Transcriptomic analysis showed concurrent downregulation of lipid and peroxisome pathways during ASA challenge in N‐ERD patients after 24 weeks of
Julia Eckl‐Dorna   +10 more
wiley   +1 more source

A Risk or a Buffer? The Dual Role of Poverty in Community Perceptions of Child Protection Demand

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT The relationship between poverty and child protection demand is complex. Using macro‐level data from 293 Finnish municipalities, this study applies hierarchical linear regression and mediation analysis to examine how poverty shapes community perceptions of child protection demand. The hierarchical linear regression findings reveal that poverty
Ning Zhu   +3 more
wiley   +1 more source

Five Years Follow-up of Imlifidase Desensitized Kidney Transplant Recipients. [PDF]

open access: yesTranspl Int
Lorant T   +11 more
europepmc   +1 more source

[Desensitization].

open access: yesRevue de l'infirmiere, 1996
V, Boucher   +3 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy