Results 151 to 160 of about 2,288,448 (331)

Outcome of Emergent ABO-Incompatible Liver Transplantation is Acceptable but at the Cost of Higher Diffuse Intrahepatic Biliary Stricture: A Single-Center, Retrospective Study

Therapeutics and Clinical Risk Management
Junfang Liu,1,2,* Jiameng Qi,3,* Ying Chen,1,2,* Xin Duan,1,2 Xinyu Yu,1,2 Pingbo Jin,1,2 Yuntao Zhang,1,2 Wei Zhang1,2 1Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, Zhejiang University School
Liu J, Qi J, Chen Y, Duan X, Yu X, Jin P, Zhang Y, Zhang W   +7 more
doaj  

In Vitro Reconstruction of Axonal Heat Sensing with a Photothermal Nerve‐on‐a‐Chip

Small, EarlyView.
A photothermal nerve‐on‐a‐chip platform is presented that enables precise, localized heating of sensory axons with simultaneous electrical recording. The system reveals millisecond‐scale dynamics of heat‐evoked neural activity and provides a new approach to study how temperature‐dependent ion channel behavior is translated into axonal firing.
Koji Sakai, Yujiro Tanaka, Riku Takahashi, Toichiro Goto, Yosuke Mizuno, Taiki Otomo, Aya Tanaka   +6 more
wiley   +1 more source

Possible Involvement of Lysophospholipids in Severe Asthma as Novel Lipid Mediators

Biomolecules
In severe asthma, symptoms are unstable despite intensive treatment based on high doses of inhaled corticosteroids and on-demand use of oral corticosteroids.
Hiroaki Kume, Kentaro Kazama, Riko Sato, Yuki Sato   +3 more
doaj   +1 more source

Preliminary investigation of equine veterinary hospital staff attitudes towards pain assessment in a single centre

Veterinary Record, EarlyView.
Abstract Background Despite the availability of several equine pain assessment tools, their use in equine veterinary practice appears limited compared to small animal practice. This study explores potential barriers to equine pain assessment, as reported by staff at a single UK equine teaching hospital.
Olivia Curry, Alice Everett, Gemma Pearson, Cathy Dwyer, Juliet Duncan   +4 more
wiley   +1 more source

Clinical characteristics of immediate allergic adverse reactions to intravenous amoxicillin‒clavulanic acid in conscious dogs

Veterinary Record, EarlyView.
Abstract Background Amoxicillin‒clavulanic acid (AMC) is one of the most frequently used antibiotics in small animal practice, and reports on adverse reactions are scarce. The aim of this study was to describe the clinical characteristics of immediate allergic adverse reactions to intravenous (IV) AMC in conscious dogs. Methods The medical records of a
Leonel Frutuoso, Anna Threlfall
wiley   +1 more source

Randomized controlled trial investigating web-based, therapist delivered eye movement desensitization and reprocessing for adults with suicidal ideation

Frontiers in Psychiatry
IntroductionPromising preliminary evidence suggests that EMDR may reduce suicidal ideation (SI) when used to treat Major Depressive Disorder, Posttraumatic Stress Disorder, and trauma symptoms in the context of acute mental health crises.
Lisa Burback, Lisa Burback, Lisa Burback, Sidney Yap, Scot E. Purdon, Adam Abba-Aji, Adam Abba-Aji, Katie O’Shea, Suzette Brémault-Phillips, Suzette Brémault-Phillips, Andrew J. Greenshaw, Olga Winkler, Olga Winkler, Olga Winkler   +13 more
doaj   +1 more source

Pathophysiological role of extrasynaptic GABAA receptors in typical absence epilepsy [PDF]

, 2011
GABA is the principal inhibitory neurotransmitter in the mammalian CNS. It acts via two classes of receptors, the GABAA, a ligand gated ion channel (ionotropic receptor) and the metabotropic G-protein coupled GABAB receptor.
Crunelli, Vincenzo, Di Giovanni, Giuseppe, Errington, Adam C.   +2 more
core  

Abattoir antemortem inspection protocol: Observation of unloading improves detection of transport welfare compromises in livestock

Veterinary Record, EarlyView.
Abstract Background Ensuring livestock welfare throughout the production chain, including transport, is an ethical and regulatory imperative. However, protocols to assess transport‐related welfare during routine abattoir inspections are not standardised, including antemortem (AM) inspection by an official veterinarian at UK abattoirs.
Sayaka Mochizuki, Declan Arden, Kurt Arden   +2 more
wiley   +1 more source

Lateral Habenula contribution in Nicotine addiction : focus on Dopamine, GABA and Serotonin Interactions [PDF]

, 2011
Compelling evidence has shown a pivotal role of dopaminergic function in drug addiction. Recently, the Habenula (Hb) has attracted a great deal of attention as another target for nicotine in the brain because of its role in regulating dopamine (DA ...
Benigno, Arcangelo, Di Giovanni, Giuseppe, Muscat, Richard, Pierucci, Massimo, Pitruzzella, Alessandro, Valentino, Mario, Zammit, Christian   +6 more
core   +1 more source

The multifaceted functions of β-arrestins and their therapeutic potential in neurodegenerative diseases

Experimental and Molecular Medicine
Arrestins are multifunctional proteins that regulate G-protein-coupled receptor (GPCR) desensitization, signaling, and internalization. The arrestin family consists of four subtypes: visual arrestin1, β-arrestin1, β-arrestin2, and visual arrestin-4 ...
Teresa R Kee, Sophia A. Khan, Maya B. Neidhart, Brianna M. Masters, Victoria K Zhao, Yenna K Kim, Kyle C McGill Percy, Jung-A A. Woo   +7 more
semanticscholar   +1 more source