Results 51 to 60 of about 1,746 (156)

Kinetic Fingerprints as Mechanistic and Clinical Roadmaps Across KIT Activation States

ChemMedChem, Volume 21, Issue 11, 15 June 2026.
Kinetic profiling of 172 compounds across KIT conformations—including D816V—reveals kinetic fingerprints that predict efficacy, selectivity, resistance, and inhibitors’ ability to stabilize key regulatory elements. Far from a secondary metric, binding kinetics provide mechanistic insights beyond affinity, offering a powerful framework for rational drug
Ana Corrionero, Niall Prendiville, Tatiana Cazorla, Maria Baena‐Nuevo, Röhm Sandra, Emilio Camafeita, Stefan Knapp, Patricia Alfonso   +7 more
wiley   +1 more source

Simulating drying and human impacts on river networks to evaluate biological quality indices performance through the lens of metacommunity theory

Journal of Applied Ecology, Volume 63, Issue 5, May 2026.
This work constitutes a first step towards developing simulation‐based assessments that incorporate catchment drying patterns to support biomonitoring of drying river networks. Our approach can inform stakeholders when current methods are likely to fail and contribute to decision‐making on whether adapting current methods is possible or developing new ...
Zeynep Ersoy, David Cunillera‐Montcusí, Martí Piñero‐Fernández, Miguel Cañedo‐Argüelles, María Mar Sánchez‐Montoya, Núria Bonada, Núria Cid   +6 more
wiley   +1 more source

A full-system direct weighing method with diet-stratified sampling for hospital food waste quantification

MethodsX
Direct weighing enables precise quantification of hospital food waste, but its implementation across an entire hospital food service system presents substantial operational challenges. This article presents a comprehensive measurement methodology aligned
Tianyu Zhang-Jin, Djamel Rahmani, José M. Gil   +2 more
doaj   +1 more source

Canvi industrial i projectes de desenvolupament al Bages i al Berguedà 1975-1998. Contribució a una teoria del desenvolupament local en l’espai en xarxa

Documents d'Anàlisi Geogràfica, 2004
LLUSSÀ I TORRA, Rafael Canvi industrial i projectes de desenvolupament al Bages i al Berguedà 1975-1998. Contribució a una teoria del desenvolupament local en l’espai en xarxa Manresa: Centre d’Estudis del Bages, 2002 (Monogràfics, 24); 329 p.
Pau Alegre Nadal
doaj   +1 more source

Effects of feeding almond hulls to light lambs on carcass characteristics and meat quality

Journal of the Science of Food and Agriculture, Volume 106, Issue 6, Page 3876-3884, April 2026.
Abstract BACKGROUND Almond hulls (AH) are the main by‐product of almond processing for human consumption and contain bioactive compounds that can improve meat quality. Although AH are used as feed for dairy cows in some countries, information on their potential effects on meat quality is limited.
Adriana Recalde, Trinidad de Evan, Almudena Cabezas, María Teresa Díaz‐Chirón, Javier Mateo, Rafael A. Roldán, Silvia López‐Feria, María Dolores Carro   +7 more
wiley   +1 more source

El govern d'Internet

IDP, 2006
L'escrit planteja una anàlisi de la temàtica del govern d'Internet, des del fenomen de la societat de la informació, en què l'eix bàsic del desenvolupament de polítiques ha d'estar basat en l'ésser humà.
Erick Iriarte
doaj   +1 more source

When honeybees come to town: Critical aspects of urban beekeeping and opportunities for regulation

People and Nature, Volume 8, Issue 3, Page 528-540, March 2026.
Abstract Urban areas are increasingly valued for their role in conserving wild pollinators. Honeybees are often regarded as ambassador species for pollinator conservation, and beekeeping is frequently perceived as a pro‐biodiversity activity, which has become highly popular in urban areas.
Joan Casanelles‐Abella, Katherine Baldock, Sara Diana Leonhardt, Marco Moretti, Mark Patterson, Monika Egerer   +5 more
wiley   +1 more source

Soil ecosystem function loss under traditional gold mining landscapes in Tigray, Ethiopia: A function‐based soil quality indices approach

Soil Science Society of America Journal, Volume 90, Issue 2, March/April 2026.
Abstract Traditional gold mining (TGM) contributes to land degradation, yet its impacts on key soil ecosystem functions remain poorly understood. This study investigated soil degradation caused by TGM in Tigray, Ethiopia, to identify sensitive soil quality indicators and develop function‐based soil quality indices (SQIs), compare soil quality scoring ...
Meaza Zenebe, Tesfay Araya, Mitiku Haile, Tewodros Tadesse, Kassa Teka, Emiru Birhane   +5 more
wiley   +1 more source

The Gut Microbiota as a Mediator in the Relationship Between Dietary Patterns and Depression

MedComm, Volume 7, Issue 2, February 2026.
Healthy dietary patterns are associated with gut microbial genera linked to lower depressive symptoms. In 644 older adults from the PREDIMED‐Plus cohort, 16S rRNA sequencing and dietary scoring revealed that taxa associated with a better diet quality were also more abundant in individuals with fewer depressive symptoms.
Adrián Hernández‐Cacho, Jiaqi Ni, Jesús F. García‐Gavilán, Prokopis Konstanti, Clara Belzer, Jesús Vioque, Dolores Corella, Montserrat Fitó, Josep Vidal, Laura Torres‐Collado, Oscar Coltell, Nancy Babio, Javier Hernando‐Redondo, Isabel Moreno‐Indias, Miguel Ruiz‐Canela, Francisco J. Tinahones, Jordi Salas‐Salvadó   +16 more
wiley   +1 more source

Urbanització sense desenvolupament

, 2020
What is the relationship between urbanization and economic development? Historically, both processes have gone hand in hand; developed countries are today also the most urbanized. However, during the last decades, many developing countries, especially in Sub-Saharan Africa, have undergone accelerated urbanization processes not necessarily associated ...
openaire   +1 more source