Results 51 to 60 of about 7,374 (209)

Nutraceutical Blends Promote Weight Loss, Inflammation Reduction, and Better Sleep: The Role of Faecalibacterium prausnitzii in Overweight Adults–A Double‐Blind Trial

Molecular Nutrition &Food Research, Volume 69, Issue 17, September 2025.
This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina, Victor Nehmi Filho, Jéssica Alves de Freitas, Lucas Augusto Moysés Franco, Roberta Cristina Martins, Joyce Vanessa Fonseca, José Antônio Orellana Turri, Mariana Tedesco Hufnagel, Daniel Pecoraro Demarque, Bruna Fernanda Rio Branco da Silva, Arianne Fagotti Gusmão, Eloísa Helena Ribeiro Olivieri, Erica de Souza, Esther Alves de Souza, José Pinhata Otoch, Ana Flávia Marçal Pessoa   +15 more
wiley   +1 more source

APLICAÇÃO DO CUSTO-META COMO FERRAMENTA DE APOIO NO DESENVOLVIMENTO DE NOVOS PRODUTOS: UM ESTUDO DE CASO EM INDÚSTRIA DE LATICÍNIOS

ABCustos, 2018
O acirramento da competitividade nos mercados e o surgimento de um consumidor moderno, com novos hábitos e mais exigente, principalmente em relação a preço e qualidade dos produtos, tem exigido cada vez mais das empresas a adoção de estratégias que as ...
Jessica Barros Anastácio, Francisco Délio Pereira de Souza, Renato Silveira de Oliveira, Leonardo Fabris Lugoboni, Marcus Vinicius Moreira Zittei   +4 more
doaj   +1 more source

Modelos de Desenvolvimento de Produto e Aplicações Gerenciais

, 2023
O Livro fala sobre modelos de gestão de desenvolvimento de ...
Moreira, Luis Fernando, Vidor, Gabriel, Panizzon, Mateus   +2 more
openaire   +1 more source

Antibiotic‐Induced Dysbiosis of the Gut Microbiota Shifts Host Tryptophan Metabolism and Increases the Susceptibility of Mice to Pulmonary Infection With Pseudomonas aeruginosa

Immunology, Volume 175, Issue 4, Page 453-466, August 2025.
Antibiotic‐induced dysbiosis of the gut microbiota shifts host tryptophan metabolism and impairs the innate immune response during Pseudomonas aeruginosa pulmonary infection. (A) Eubiosis: During eubiosis, the intestinal microbiota metabolises tryptophan into indole metabolites, which keeps tryptophan levels within normal serum concentrations. However,
Camila Bernardo de Brito, Raquel Duque do Nascimento Arifa, Rafael de Oliveira Bezerra, Carlos Eduardo Dias Igídio, Bárbara Maria de Amorim‐Santos, Anna Clara Paiva de Menezes Santos, Larissa Mendes Barbosa, João Paulo Pezzini Barbosa, Larissa Marcely Gomes Cassiano, Markus Kohlhoff, Micheli Fagundes, Rafaela Ribeiro Álvares Batista, Celso Martins Queiroz‐Junior, Alessandra M. Saliba, Juliana Divina Almeida Raposo, Fernão Castro Braga, Roney Santos Coimbra, Mauro Martins Teixeira, Caio Tavares Fagundes, Danielle G. Souza   +19 more
wiley   +1 more source

Intracellular and Extracellular Efficacy of Homoisoflavone Derivatives Against Mycobacterium Tuberculosis: Progress Toward Novel Antitubercular Agents

ChemMedChem, Volume 20, Issue 14, July 18, 2025.
A series of 42 homoisoflavones were synthesized and evaluated against Mycobacterium tuberculosis (Mtb). Three derivatives showed potent inhibition of Mtb strains. Evaluation in infected macrophages revealed promising intracellular activity, where one derivative featuring a nitrofuranyl and piperidine group emerges as the most promising.
Sanderson D. Calixto, Juliane S. Falcão, Stella S. Antunes, Marlon H. Araujo, Alexandre L. B. Cunha, David R. Martins, Sarah M. R. Nascimento, Thatiana L. B. V. Simão, Elena B. Lasunskaia, Nelilma C. Romeiro, Paulo R. R. Costa, Michelle F. Muzitano, Guilherme S. Caleffi   +12 more
wiley   +1 more source

Synthesis of biofuel esters catalyzed by lipase B from Candida antarctica immobilized on a magnetic lignin‐based support derived from cashew apple bagasse

Biofuels, Bioproducts and Biorefining, Volume 19, Issue 4, Page 1165-1173, July/August 2025.
Abstract This study investigated the biosynthesis of ethyl oleate (EO), the main constituent of biodiesel, via the esterification of oleic acid with ethanol, catalyzed by Candida antarctica lipase B (CALB) immobilized on a low‐cost support derived from cashew apple bagasse (CAB) lignin.
Hilldyson Moreira Levy, Tigressa Helena Soares Rodrigues, Tiago Lima de Albuquerque, Hosiberto Batista Sant’Ana, Filipe Xavier Feitosa, Maria Valderez Ponte Rocha   +5 more
wiley   +1 more source

The Rapid Recovery of a Caatinga Dry Forest is Mediated by Disturbance‐Adapted Species

Biotropica, Volume 57, Issue 4, July 2025.
Overall, regenerating and old‐growth forest stands exhibited similar plant diversity across all ontogenetic stages, with a negligible role played by forest stand age, precipitation, and chronic human disturbance. Species exclusively recorded as adults or seeds were mostly dispersed by animals, indicating that several species fail in either dispersing ...
Alexandre S. de Paula, Marcelo Tabarelli, Diego P. F. Trindade, Maria Fabíola Barros, Kátia F. Rito, Danielle G. Souza, Julia C. Sfair   +6 more
wiley   +1 more source

In Vitro and In Silico Evaluation of Isatin‐Derived Spirooxindoles as Antituberculosis Drug Candidates

Chemical Biology &Drug Design, Volume 106, Issue 1, July 2025.
Two compounds, A16 and A17, were active against multidrug‐resistant Mycobacterium tuberculosis isolates (PT‐12 and PT‐20), overcoming key resistance mutations in katG and rpoB, while cytotoxicity assays confirmed that they are non‐toxic. A17 exhibited the highest antituberculosis activity, with molecular docking suggesting enoyl‐[acyl‐carrier‐protein ...
Fernanda Rodrigues de Lima, Jéssika de Oliveira Viana, Aleff Cruz de Castro, Rodrigo Cristiano, Marcia Alberton Perelló, Alexia de Matos Czeczot, Cristiano Valim Bizarro, Pablo Machado, Luiz Augusto Basso, Claudio Gabriel Lima‐Junior, Valnês da Silva Rodrigues‐Junior, Karen Cacilda Weber   +11 more
wiley   +1 more source

Novel 2-Thiazolylhydrazone with Druggable Properties for Antifungal Application

Journal of Fungi
Fungal infections have become a growing concern in healthcare, particularly in immunocompromised individuals, with species like Candida, Cryptococcus, and Sporothrix posing significant challenges due to rising resistance and limited treatment options. In
Wallace Cordeiro de Morais, Gustavo Henrique Oliveira Costa, Vinícius Leal Pitcella, João Victor Vanolli Protti, Carolina Paula de Souza Moreira, José Eduardo Gonçalves, Susana Johann, Renata Barbosa de Oliveira   +7 more
doaj   +1 more source

Uso do amido de milho, farinha de arroz e farelo de cacau no desenvolvimento de produtos glúten free / Use of corn starch, rice flour and cocoa bran in the development of gluten free products

, 2022
Jessanna Dias Sarques Bellini, Luíz Guilherme Malaquias da Silva, Maria das Graças de Souza Carvalho, Bethânia Elias Costa, José Antônio Dias Garcia, Aline Manke Nachtigall   +5 more
openalex   +1 more source