Results 101 to 110 of about 661,394 (254)
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
ARQ, 2004 Durante el siglo XX el aire seco y cierta benevolencia del clima hicieron de una parte del oeste de EE.UU. el campo ideal para las experiencias de arquitectos como Albert Frey o Rudolph Schindler.
Rick Joy
doaj
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Long‐term effects of land‐use change on bird communities depend on spatial scale and land‐use type
Ecosphere, 2019 Land‐use transformation is one of the most important and pervasive ecological changes occurring across the Earth, but its long‐term effects are poorly understood.
Daniel C. Allen +5 more
doaj +1 more source
Point irrigation for locality Buchel in the north desert Gobi in Mongolia
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2009 The design of point irrigation, created by Filip et al. (2007), was worked up as the bilateral projekt in the frame of abroad developing cooperation between the Czech Republic and Mongolia „Rehabilitation of plant production in semiarid territories of ...
Pavel Spitz, Jiří Filip
doaj +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Justice, markets, and the family
Erasmus Journal for Philosophy and Economics, 2016 The Erasmus Journal for Philosophy and Economics interviewed Olsaretti about becoming a political philosopher, her work on the ethics of markets and justice and the family, the ERC-project that she directs, her views on teaching, and her advice for ...
Serena Olsaretti
doaj +1 more source