Results 81 to 90 of about 235,424 (288)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Family empowerment towards sustainable desert settlements : the Family Wellbeing Empowerment program in Alice Springs

open access: yes, 2009
Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT).Family empowerment towards sustainable desert settlements: the Family Wellbeing Program in Alice Springs -- FWB in Alice Springs -- Discussion ...
Desert Knowledge Cooperative Research Centre (Australia)   +1 more
core  

Psychology of Deserters [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1922
n ...
openaire   +2 more sources

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Tres proyectos en Arizona

open access: yesARQ, 2004
Durante el siglo XX el aire seco y cierta benevolencia del clima hicieron de una parte del oeste de EE.UU. el campo ideal para las experiencias de arquitectos como Albert Frey o Rudolph Schindler.
Rick Joy
doaj  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Long‐term effects of land‐use change on bird communities depend on spatial scale and land‐use type

open access: yesEcosphere, 2019
Land‐use transformation is one of the most important and pervasive ecological changes occurring across the Earth, but its long‐term effects are poorly understood.
Daniel C. Allen   +5 more
doaj   +1 more source

Point irrigation for locality Buchel in the north desert Gobi in Mongolia

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2009
The design of point irrigation, created by Filip et al. (2007), was worked up as the bilateral projekt in the frame of abroad developing cooperation between the Czech Republic and Mongolia „Rehabilitation of plant production in semiarid territories of ...
Pavel Spitz, Jiří Filip
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

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