Results 81 to 90 of about 661,394 (254)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Review of Flying to Victory: Raymond Collishaw and the Western Desert Campaign, 1940-1941 by Mike Bechthold [PDF]
, 2019 Review of Flying to Victory: Raymond Collishaw and the Western Desert Campaign, 1940-1941 by Mike ...
Stubbs, David
core +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Emission from small dust particles in diffuse and molecular cloud medium [PDF]
Infrared Astronomy Satellite (IRAS) observations of the whole galaxy has shown that long wavelength emission (100 and 60 micron bands) can be explained by thermal emission from big grains (approx 0.1 micron) radiating at their equilibrium temperature ...
Bernard, J. P., Desert, X.
core +1 more source
Collapse of a desert bird community over the past century driven by climate change [PDF]
, 2020 Climate change has caused deserts, already defined by climatic extremes, to warm and dry more rapidly than other ecoregions in the contiguous United States over the last 50 years.
Beissinger, Steven R., Iknayan, Kelly J.
core
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Biotic Interactions in Experimental Antarctic Soil Microcosms Vary with Abiotic Stress
Soil Systems, 2019 Biotic interactions structure ecological communities but abiotic factors affect the strength of these relationships. These interactions are difficult to study in soils due to their vast biodiversity and the many environmental factors that affect soil ...
E. Ashley Shaw, Diana H. Wall
doaj +1 more source
The Judean desert monasteries in the Byzantine period [PDF]
, 1996 Reviewed Book: Hirschfeld, Yizhar. The Judean desert monasteries in the Byzantine period.
Baglole, Kevin J.
core +1 more source
Substellar Companions to Main Sequence Stars: No Brown Dwarf Desert at Wide Separations
, 2001 We use three field L and T dwarfs which were discovered to be wide companions to known stars by the Two Micron All-Sky Survey (2MASS) to derive a preliminary brown dwarf companion frequency.
Adam Burgasser +10 more
core +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source