Results 61 to 70 of about 242,610 (251)
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
The high cost of movement in an arid working landscape for an endangered amphibian
Ecology and EvolutionConnectivity is essential for the maintenance of genetic diversity and stability of wildlife populations. Drought and changing precipitation regimes have caused natural aquatic amphibian breeding habitats to disappear or become isolated and have led to ...
Colin W. Brocka +2 more
doaj +1 more source
Mise en ligne du carnet de recherche "Desert Networks"
, 2018 Nous avons le plaisir de lancer aujourd'hui le carnet de recherche Desert Networks. Il vise à présenter la problématique, l'équipe, les travaux en cours ainsi que les résultats du projet « Desert Networks: Into the Eastern Desert of Egypt from the New ...
Desert Networks
core
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Le projet ERC Desert Networks dans la lettre de l'INSHS
, 2019 Les enjeux et les réalisations du projet Desert Networks sont à l'honneur dans la lettre d'information de l'INSHS (Institut des sciences humaines et sociales du CNRS) !
Desert Networks
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Biotic Interactions in Experimental Antarctic Soil Microcosms Vary with Abiotic Stress
Soil Systems, 2019 Biotic interactions structure ecological communities but abiotic factors affect the strength of these relationships. These interactions are difficult to study in soils due to their vast biodiversity and the many environmental factors that affect soil ...
E. Ashley Shaw, Diana H. Wall
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The influence of ambient conditions on a person's socio-political maturation: Example of the blessed Muhammad: A citizen of the world par excellence [PDF]
Kom: Časopis za Religijske NaukeIn the paper, we plan to examine how different ambient conditions and social conditioning affect a person's socio-political maturation in layers, to such an extent that sometimes the mentioned maturations are not only not identical, but almost not even ...
Dizdarević Bajram, Efendić Davud
doaj +1 more source