Results 41 to 50 of about 242,610 (251)

How Much Punishment Is Deserved? Two Alternatives to Proportionality

open access: yesPhilosophies, 2022
When it comes to the question of how much the state ought to punish a given offender, the standard understanding of the desert theory for centuries has been that it should give him a penalty proportionate to his offense, that is, an amount of punishment ...
Thaddeus Metz, Mika’il Metz
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Between Absolute and Fluid Space: the Representation of the Oasis

open access: yesDiségno, 2019
At the edge of the desert, near the wetlands, the palm grew in small wild spots that reproduced by the action of the wind, forming a favorable environment for human settlement.
Paola Raffa
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Patterns in Habitat Type, Species Richness and Community Composition at Avdat Lter, Israel

open access: yesJournal of Landscape Ecology, 2012
The EBONE (European Biodiversity Observation Network project) asked the Israel Nature and Parks Authority to test methodology correlating patterns of species distribution with habitat in arid regions. A test of this methodology was conducted at the Avdat
Olsvig-Whittaker Linda   +3 more
doaj   +1 more source

Determination of Iran Desert Lands Based on Soil Attributes [PDF]

open access: yesمدیریت بیابان, 2013
Deserts have been described in different aspects of the natural environment. In this article, we try to determine desert territory using soil properties.
Mohammad Khosroshahi   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Effects of Hedysarum leguminous plants on soil bacterial communities in the Mu Us Desert, northwest China

open access: yesEcology and Evolution, 2020
This study assessed the influence of rhizocompartment types (i.e., root, rhizosphere soil, root‐zone soil, and intershrub bulk soil) on the diversity of soil microbial communities under desert leguminous plant shrubs.
Ziyuan Zhou   +5 more
doaj   +1 more source

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