Results 41 to 50 of about 8,770 (243)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Pesquisa Agropecuária Brasileira, 2007 O objetivo deste trabalho foi avaliar o impacto da antecipação da colheita de lavouras de cevada sobre a germinação dos grãos, ao longo de 12 meses de armazenamento. O ensaio de campo foi realizado em 2002 e 2003.
Eduardo Caierão, Adão da Silva Acosta
doaj +1 more source
Energies, 2020 In this study, experimental apparatus of desiccant dehumidification was developed at lab-scale, using silica gel as a desiccant material. Experimental data were obtained at various ambient air conditions, while focusing the climatic conditions of Multan (
Muhammad Aleem +8 more
doaj +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Experimental investigation of a mixed desiccant solution of potassium formate and ionic liquid
Green Energy and SustainabilityLiquid desiccant technology is a promising energy-efficient alternative to conventional temperature and humidity control systems. In the quest to identify the optimal fluid for liquid desiccant systems, alternative desiccant solutions have been explored ...
Dingming Jiang +3 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Design of ionic liquids as liquid desiccant for an air conditioning system
Green Energy & Environment, 2019 Suitable control of the humidity can contribute to electric energy savings. However, the present dehumidification system has many weak points. The liquid desiccant air-conditioning system has recently gained growing interest from the stand point of ...
Haruki Watanabe +6 more
doaj +1 more source
Applied Sciences, 2020 The dynamic capacity of the commercial desiccant (NaX zeolite) and the adsorbent, synthesised based on low-temperature modifications of aluminium oxide, obtained from bayerite-containing hydroxide, was determined with respect to water vapour ...
Eugene Meshcheryakov +5 more
doaj +1 more source