Results 141 to 150 of about 379 (257)

A Three‐Dimensional Culture–Drug Sensitivity Test Predicts MDM2 Inhibitor–Sensitivity in SMARCB1/INI1‐Deficient Tumors

open access: yesCancer Science, EarlyView.
This study aimed to determine whether personalized selection of effective drugs for SMARCB1/INI1‐deficient tumors is feasible using in vitro drug sensitivity profiling. Drug sensitivity was assessed using a short‐term collagen gel–embedded three‐dimensional drug sensitivity test (3D‐DST) in tumors derived from SMARCB1/INI1‐deficient tumor cell line ...
Hiroaki Goto   +12 more
wiley   +1 more source

Randomised Clinical Trial to Evaluate the Efficacy of Acetazolamide for the Treatment of Cystoid Fluid Collections in X‐Linked Retinoschisis: The AXIS Trial

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background This trial aimed to evaluate the efficacy of oral acetazolamide in reducing cystoid fluid collections (CFC) and improving visual function in patients with X‐linked retinoschisis (XLRS). Methods In this investigator‐initiated, single centre, open‐label, randomised controlled trial, XLRS patients aged ≥ 12 years with fovea‐involving ...
Jonathan Hensman   +15 more
wiley   +1 more source

Mixed Super‐Circles

open access: yesComputer Graphics Forum, EarlyView.
Abstract We introduce mixed super‐circles, a position‐curvature formulation of the original dynamic 2D super‐helix model. Compared to the latter, purely curvature‐based model – the so‐called chained formulation –, the mixed formulation that we propose here drastically reduces the algorithmic complexity of the solving scheme – from quadratic to quasi ...
Emile Hohnadel   +2 more
wiley   +1 more source

Water Vapor Adsorption-Desorption Behavior of Surfactant-Coated Starch Particles for Commercial Energy Wheels. [PDF]

open access: yesACS Omega, 2019
Shakouri M   +5 more
europepmc   +1 more source

‘Elbow grease and yellow soap’: Housework time in working‐class households in late‐nineteenth and early twentieth‐century Britain

open access: yesThe Economic History Review, EarlyView.
Abstract Housework is central to feminist calls for recognition of women's work, economic histories explaining the sexual division of labour, and claims regarding the progressive role of scientific knowledge. Yet little is known about the time it actually took. We address this lacuna.
Sara Horrell, Jane Humphries
wiley   +1 more source

Ceramic ecology in an Islamic capital: changes in the production and consumption of pottery in Palermo

open access: yesEarly Medieval Europe, EarlyView.
Palermo became the new capital of Sicily after the Aghlabid conquest in 831. The transformation of the city into a capital took many forms, including the production and consumption of pottery. The perspective from ceramic evidence shows that Palermo underwent faster and deeper processes of Islamization than other urban and rural contexts across the ...
Viva Sacco
wiley   +1 more source

Circadian disruption elicits sex‐specific gut microbiota, endocannabinoidome, and lipid mediator responses

open access: yesThe FEBS Journal, EarlyView.
Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy