Results 71 to 80 of about 74,537 (310)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Desiccation-induced viable but nonculturable state in Pseudomonas putida KT2440, a survival strategy - Fig 13

open access: yes, 2019
Gene expression levels of mutL (blue bar), mutS (orange bar) and oprH (gray bar) obtained by RT-qPCR. Before desiccation (0) and 6, 12 and 18 DABD.
Osvaldo Rodríguez-Andrade (4579561)   +12 more
core   +1 more source

Plant desiccation tolerance and its regulation in the foliage of resurrection “Flowering-Plant” species [PDF]

open access: yes, 2018
The majority of flowering-plant species can survive complete air-dryness in their seed and/or pollen. Relatively few species (‘resurrection plants’) express this desiccation tolerance in their foliage. Knowledge of the regulation of desiccation tolerance
Hamill, J. D.   +19 more
core   +1 more source

On the Desiccation of Eurasia and Some General Aspects of Desiccation [PDF]

open access: yesThe Geographical Journal, 1914
n ...
Kropotkin, P.   +2 more
openaire   +1 more source

Induction of desiccation tolerance in desiccation sensitive Citrus limon seeds [PDF]

open access: yesJournal of Integrative Plant Biology, 2019
AbstractMany economically important perennial species bear recalcitrant seeds, including tea, coffee, cocoa, mango, citrus, rubber, oil palm and coconut. Orthodox seeds can be dried almost completely without losing viability, but so‐called recalcitrant seeds have a very limited storage life and die upon drying below a higher critical moisture content ...
Marques, Alexandre   +4 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Susceptibility of Perennial Tropical Forage Plants to Glyphosate Herbicide in Integrated Crop-Livestock Farming Systems [PDF]

open access: yesPlanta Daninha, 2018
: The purpose of this study was to evaluate forage plant susceptibility in Urochloa ssp. and Megathyrsus maximus with two glyphosate herbicide doses, to increase the efficiency of integrated crop-livestock farming systems.
L.A.Z. MACHADO   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Ionotropic Receptor-dependent moist and dry cells control hygrosensation in Drosophila

open access: yeseLife, 2017
Insects use hygrosensation (humidity sensing) to avoid desiccation and, in vectors such as mosquitoes, to locate vertebrate hosts. Sensory neurons activated by either dry or moist air (‘dry cells’ and ‘moist cells’) have been described in many insects ...
Zachary A Knecht   +6 more
doaj   +1 more source

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