Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Heat and desiccation tolerances of Heterorhabditis bacteriophora strains and relationships between their tolerances and some bioecological characteristics [PDF]
Invertebrate Survival Journal, 2014 Heat tolerances, desiccation tolerances, and effectiveness of 10 Heterorhabditis bacteriophora strains isolated from different climatic regions in Turkey were analyzed in laboratory conditions.
TC Ulu, IA Susurluk
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Dehydration-induced Ae-Aper50 regulates midgut infection in Aedes aegypti mosquitoes
mBioClimate change is predicted to increase the spread of mosquito-borne viruses, but genetic mechanisms underlying the influence of environmental variation on the ability of insect vectors to transmit human pathogens is unknown.
Anastasia Accoti +8 more
doaj +1 more source
Characterization of the Desiccation Tolerance of Cronobacter sakazakii Strains
Frontiers in Microbiology, 2018 Strong desiccation tolerance is an outstanding feature of Cronobacter sakazakii and can enable the bacterium to survive in a dry food matrix (such as milk powder) for a long time.
Xin-jun Du +5 more
doaj +1 more source
Numerical analysis of desiccation, shrinkage and cracking in low plasticity clayey soils [PDF]
, 2017 This paper presents a numerical study of the desiccation processes of low-plasticity clayey soils that usually result in shrinkage and often in cracking.
Ledesma Villalba, Alberto +2 more
core
Hydraulic conductivity of a dense prehydrated geosynthetic clay liner [PDF]
, 2015 Dense prehydrated geosynthetic clay liners (DPH-GCLs) are a particular type of GCL which, unlike conventional GCLs manufactured with dry bentonite, contain bentonite prehydrated during manufacturing.
Di Emidio, Gemmina, Mazzieri, Francesco
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Yantu gongcheng xuebaoTo explore the development process of desiccation cracking in clay soil, the desiccation cracking deterioration on the surface of the archaeological site in sacrifice area of Sanxingdui Ruins site is taken as the research object.
ZHAO Fan 1, YAO Xue 2, HU Rui 1, LI Sifan 1, LI Junhao 1
doaj +1 more source
Survival and behavior of Chinese mystery snails (Bellamya chinensis) in response to simulated water body drawdowns and extended air exposure [PDF]
Management of Biological Invasions, 2013 Nonnative invasive mollusks degrade aquatic ecosystems and induce economic losses worldwide. Extended air exposure through water bodydrawdown is one management action used for control.
Kody M. Unstad +7 more
doaj +1 more source