Results 171 to 180 of about 56,912 (284)

Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash, Jacob Robins, J. Scott VanEpps, Minji Kim, Jouha Min   +4 more
wiley   +1 more source

Desiccation-tolerance and globular proteins adsorb similar amounts of water. [PDF]

Protein Sci, 2022
Brom JA, Pielak GJ.
europepmc   +1 more source

Cyclic Peptide–Polymer Conjugate Nanotubes for Delivery of SN‐38 in Treatment of Colorectal Cancer Model

Advanced Healthcare Materials, EarlyView.
This study develops cyclic peptidepolymer conjugate nanotubes with hydrophobic, drug‐rich cores to enhance drug loading and stability, and demonstrates their responsive disassembly, pharmacokinetics, and anti‐tumour efficacy in colorectal cancer models using the anticancer drug SN‐38.
Sophie K. Hill, Min Zeng, Santhosh Kalash Rajendrakumar, Robert Dallmann, Sébastien Perrier   +4 more
wiley   +1 more source

Desiccation Tolerance in Moss and Liverwort: Insights into the Evolutionary Mechanisms of Terrestrialization. [PDF]

Int J Mol Sci
Ghosh TK, Nazran A, Khan I, Naimul Islam SM, Islam T, Xu Y, Mostofa MG.   +6 more
europepmc   +1 more source

A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment

Advanced Healthcare Materials, EarlyView.
A human cell‐based microphysiological system integrates engineered muscle tissues with an inflamed adipose–macrophage niche to model obese microenvironment‐induced muscle dysfunction. Muscle contraction is quantified by pillar deflection coupled with computational stiffness estimation. Secretome and transcriptomic profiling reveal inflammation‐mediated
Seunggyu Kim, Tianxin Cao, Zhengpeng Wan, Jaesang Kim, Zhuxuan Li, Legairre A. Radden II, Rakesh Santhanam, Eunkyung Clare Ko, Tatsuya Osaki, Sarah Spitz, Hyunmin Moon, Maria Proestaki, Seokbeom Roh, Gyudo Lee, Jessie S. Jeon, Curtis R. Warren, Roger D. Kamm   +16 more
wiley   +1 more source

Defying Death: A Multi-Omics Approach to Understanding Desiccation Tolerance and Senescence in <i>Eragrostis nindensis</i>. [PDF]

Plants (Basel)
Madden CF, Williams B, Mundree S, Acket S, Ruelland E, Hilhorst HWM, Farrant JM.   +6 more
europepmc   +1 more source

Trehalose and tardigrade CAHS proteins work synergistically to promote desiccation tolerance. [PDF]

Commun Biol, 2022
Nguyen K, Kc S, Gonzalez T, Tapia H, Boothby TC.   +4 more
europepmc   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

The architecture of resilience: a genome assembly of Myrothamnus flabellifolia sheds light on desiccation tolerance and sex determination. [PDF]

New Phytol
Marks RA, Lovell JT, Carey SB, Van Der Pas L, Chimukuche NM, Brůna T, Plott C, Webber J, Lipzen A, Yan J, Bauer D, Bentley J, Talag J, McLaughlin CM, Barry K, Grimwood J, Jenkins JW, Schmutz J, Harkess A, VanBuren R, Leebens-Mack J, Farrant JM.   +21 more
europepmc   +1 more source

Transcriptional profiling analysis providing insights into desiccation tolerance mechanisms of the desert moss Syntrichia caninervis. [PDF]

Front Plant Sci, 2023
Yang R, Li X, Yang Q, Zhao M, Bai W, Liang Y, Liu X, Gao B, Zhang D.   +8 more
europepmc   +1 more source