How Acoustic Environments Shape Perceived Spaciousness and Transparency in Architectural Spaces
BuildingsPeople’s perceptions of architectural spaces are shaped by multiple senses, including vision and hearing. While vision has received extensive attention, hearing is often overlooked in architectural design, with a primary focus on sound insulation and ...
Xuhui Liu, Jian Kang, Hui Ma, Chao Wang
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Promoting Pre-service Teacher Students' Learning Engagement: Design-Based Research in a Flipped Classroom. [PDF]
Front Psychol, 2022 Gu J, Tang L, Liu X, Xu J.
europepmc +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Nature-Based SolutionsWorking with nature in urban settings as a strategy for improving wellbeing offers significant potential for effective climate change adaptation. It is increasingly being explored and utilized in the region of Moananui Oceania.
Amanda Yates +2 more
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Pragmatism, design-based research and action research
, 2021 Neste artigo as autoras analisam e refletem sobre as caraterísticas de duas abordagens ligadas a uma epistemologia da prática: Design-Based Research e Investigação-Ação e o seu enquadramento no Paradigma Pragmático da investigação em Educação. A Design-Based-Research engloba um conjunto de abordagens com o objetivo de produzir novas teorias, artefactos
Pereira, Alda, Oliveira, Isolina
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Corrigendum: Innovative Pedagogy and Design-Based Research on Flipped Learning in Higher Education. [PDF]
Front Psychol, 2021 Zhao L, He W, Su YS.
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Design principles for internet skills education: results from a design-based research study in higher education. [PDF]
SN Soc Sci, 2022 Miliou O, Angeli C.
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Development and Acceptability of a Kidney Therapy Decision Aid for Patients Aged 75 Years and Older: A Design-Based Research Involving Patients, Caregivers, and a Multidisciplinary Team. [PDF]
Kidney Med, 2023 Saeed F +6 more
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