Results 91 to 100 of about 4,589,695 (260)

A framework to improve quality of hospital-based physiotherapy: a design-based research study. [PDF]

open access: yesBMC Health Serv Res, 2023
Steenbruggen RA   +4 more
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Discussions on the PhD in Art and Design with Annotated Bibliography

open access: yesCubic Journal
Motivated by Leonardo Journal (March 2018) call for papers for its PhD in Art and Design three-year symposium, the following discussion and survey of literature were undertaken to explore current international discourse on the PhD in Art and Design ...
Maria del Mar Navarro
doaj   +1 more source

The Seeing Science Project: Using Design-Based Research to Develop a Transformative Experience Intervention. [PDF]

open access: yesJ Sci Educ Technol, 2023
Pugh KJ   +6 more
europepmc   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Designing and Evaluating a Game-Based AR Application for Heritage Learning: Insights from the Choirokoitia Mystery Game

open access: yesJournal of Learning for Development
Within the trajectories of design-based research (DBR) and multimodal theory, this study captures the iterative processes undertaken to design, develop, and deploy game-based Augmented Reality (AR) applications for learning, exploration, and ...
Stella Hadjistassou   +4 more
doaj   +1 more source

The Process of Developing a Digital Repository for Online Teaching Using Design-Based Research. [PDF]

open access: yesTechTrends, 2023
Richardson JC   +3 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

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