Results 201 to 210 of about 35,808,162 (371)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

ProteinDJ: A high-performance and modular protein design pipeline. [PDF]

Protein Sci
Silke D, Iskander J, Pan J, Thompson AP, Papenfuss AT, Lucet IS, Hardy JM.   +6 more
europepmc   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Evaluating zero-shot prediction of monomeric protein design success by AlphaFold, ESMFold, and ProteinMPNN. [PDF]

Protein Sci
Garcia M, Dixit SM, Rocklin GJ.
europepmc   +1 more source

Design and the customer experience: The challenge of embodying new meaning in a new service

, 2020
Federico Artusi, Emilio Bellini
openalex   +2 more sources

Strategies of Collaborative Work in the Classroom through the Design of Video Games. [PDF]

, 2015
Juan Manuel Muñoz González, Sebastián Rubio García, Ivanovna M. Cruz Pichardo   +2 more
openalex   +1 more source

Design and Construction of Device for Rubber Material Fatigue Test

, 2021
Saddam K. Al-Raheem, Muhsin J. Jweeg, Abdul kareem F Hassan   +2 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Designing Meaningful Engagement for Older Adults: An Evaluation of Participation in a Five-Day Co-Design Sprint. [PDF]

Health Expect
Nordin S, Davis A, Légaré F, Jones A, Meijering L, Elf M.   +5 more
europepmc   +1 more source

The Systematic Design of Industrial Products through Design Archetypes: An Application on Mechanical Transmissions [PDF]

, 2020
Alberto Vergnano, Francesco Gherardini, Francesco Leali   +2 more
openalex   +1 more source