Results 61 to 70 of about 7,828,613 (296)

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

UAVs and their avionic systems: development trends and their influence on Polish research and market

Aviation, 2015
In the paper the current status of development of UAVs and their avionic systems in Poland and worldwide is presented. Technology and operation development trends, as well as key factors influencing them are described.
Cezary Szczepański
doaj   +1 more source

Designing Communication Design

The Journal of Media Innovations, 2016
Innovating in the field of new media genres requires methods for producing designs that can succeed in being disseminated and used outside of design research labs. This article uses the author's experiences with the development of university courses in communication design to address the research question: How can we design courses to give students the
openaire   +4 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Howell designs with sub-designs

Journal of Combinatorial Theory, Series A, 1994
A Howell design \(H(s,2n)\) of side \(s\) and order \(2n\), is an \(s \times s\) array in which each cell is either empty or contains an unordered pair of elements from some \((2n)\)-set \(V\) such that: (1) every element of \(V\) occurs in precisely one cell of each row and each column, and (2) every ordered pair of elements from \(V\) is in at most ...
Jeffrey H. Dinitz, E. R. Lamken
openaire   +2 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Îmbunătăţirea şi modernizarea metodelor de proiectare în domeniul acusticii construcţiilor. Programe de calcul utilizate la proiectarea acustică a sălilor de audiţie publică [PDF]

Urbanism. Arhitectura. Constructii, 2010
Manual acoustic design of the public audition halls is a complex and toilsome work. The acoustic design of new or existing audition halls, using automated programmes, is much easier as the method allows the designer to choose the optimal variant from ...
Marta Cristina Zaharia
doaj  

Design beyond Design

She Ji: The Journal of Design, Economics, and Innovation, 2019
As organizations struggle to respond to a world in which problems are becoming more open, complex and increasingly networked, many have turned to design thinking as a way to obtain solutions and achieve innovation. In this article, I will focus on the question of whether the current design paradigm is capable of delivering on these expectations, or ...
openaire   +3 more sources

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

O BRIEFING COMO FERRAMENTA AUXILIAR NA GESTÃO DE PROJETOS EM MICROEMPRESA DE PUBLICIDADE

Competência, 2014
Este artigo tem por objetivo analisar o briefing como uma ferramenta de auxílio na gestão de projetos em microempresas de design e publicidade. Para sobreviver ao período de inserção no mercado, essas empresas necessitam organização e eficácia.
Felipe Schneider Viaro, Maurício Moreira e Silva Bernardes, Régio Pierre da Silva   +2 more
doaj   +1 more source