Results 81 to 90 of about 15,545,883 (264)

The Barriers and Enablers of Co-design for Services [PDF]

open access: yes, 2016
As interest towards co-design for services in the public sector and in companies is growing, the benefits and challenges of applying it in organisations have become a topical issue.
Pirinen, Antti
core  

Exploring a Material-Focused Design Methodology: An Innovative Approach to Pressure Vessel Design

open access: yesMachines
The design of components and elements comprising industrial machinery, as well as those that are part of an industrial system, has been carried out in recent years using various design methodologies. Currently, the products demanded by customers, as well
Edgar Adhair Montes Gómez   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Constructing the future of design : How design professionals perceive their changing role

open access: yes, 2018
Design and design thinking have boomed in the past decade, expanding design considerations into new areas of application and a wide range of organizations across industry types.
Björklund, Tua A.   +2 more
core  

Development and Analysis of Six-Phase Synchronous Reluctance Motor for Increased Fault Tolerance Capabilities

open access: yesEnergies
This paper contains research on the development of a fault-tolerant six-phase synchronous reluctance motor (SynRM) based on the stator adopted from a general-purpose three-phase induction motor.
Cezary Jedryczka   +2 more
doaj   +1 more source

Strategies For Managing and Maintaining Green Infrastructure: Review [PDF]

open access: yesE3S Web of Conferences
Green spaces are essential infrastructures for improving quality of life, promoting biodiversity and responding to environmental challenges in urban areas. Their management requires a systemic approach combining strategic planning and regular maintenance.
Chkird Fadoua   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Analytical Method for the Deformation-Based Design of Retaining Walls in Asymmetric Excavation

open access: yesBuildings
Conventional methods for designing retaining structures are not applicable to asymmetric excavation or deformation-based designs. This study proposes a quadruple-line displacement-dependent earth pressure coefficient model.
Xiaozhen Fan   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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