Results 91 to 100 of about 25,875,084 (346)
ALSIC: Apprentissage des Langues et Systèmes d'Information et de Communication, 2000 This paper describes a method of developing multimedia learning environments based on a close collaboration between the client and the team of developers.
Christian Depover +2 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Il ruolo del design nella progettazione alberghiera
, 2014 l'autore è stato invitato a stendere un contributo sul ruolo del design nell'ambito della progettazione alberghiera, evidenziando le varie declinazioni della disciplina- design strategico, design dei servizi, design della comunicazione, interior design,
SCULLICA, FRANCESCO +1 more
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Overcoming Design Fixation in Idea Generation
, 2018 Ideally, designers move past existing ideas to create novel designs. But designers often experience “fixation,” where new ideas are similar to existing designs.
Seifert, Colleen +7 more
core +1 more source
Design Annual (2019-2020) [PDF]
, 2020 Design Annual is the yearly compilation of the activities and works by students and faculty at University of Central Oklahoma's School of ...
University of Central Oklahoma. School of Design.
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Exploring a Material-Focused Design Methodology: An Innovative Approach to Pressure Vessel Design
MachinesThe design of components and elements comprising industrial machinery, as well as those that are part of an industrial system, has been carried out in recent years using various design methodologies. Currently, the products demanded by customers, as well
Edgar Adhair Montes Gómez +4 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Designs, Designing, Designers, and Design Science Revisited
Design science has gained popularity in information systems. In essence, it is about designing, building, and evaluating artifacts. Despite the popularity and a lot of associated research, plenty of problems still remain. To this end, this position paper presents a critical reflection of the design science field in information systems.
openaire +1 more source