Results 111 to 120 of about 25,875,084 (346)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Local Fabric: Mid-Century Modernisms, Textile and Fashion Design, and the Northwest Coast, 1940–1967
ArtsIn the mid-twentieth century, growing North American textile and ready-to-wear industries vigorously appropriated Native American aesthetics to cultivate a commercial and design identity apart from Europe.
Laura J. Allen
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 2022 This book aims at encompassing the panorama of design tools being developed, tested and adopted by researchers and professors at the Department of Design of Politecnico di Milano.
Bruno, Carmen +4 more
core
Journal of Asian Architecture and Building EngineeringUnder the guidance of the new policy of urban renewal, the concept of community garden is gaining popularity in theory and practice in today’s increasingly tense urban environment. This paper is a review of the research on community gardens. Based on the
Ying Liu +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
, 2020 The industrial design studio presents opportunities for students to learn a range of skills and knowledge that will equip them to enter professional practice.
Berry, James Henry +11 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Design Research and Public Policy: Current Practice Working to Intersect with Government
, 2014 Design research is an academic and practical field of study that seeks to explore the ways in which design in any discipline area is produced, understood, and used.
Parliamentary Design and Innovation Group, All Party
core
Modeling the early stages of a user-centered process in architectural design through adaptation of the methodologies of New Product Design [PDF]
, 2009 In order to reach a degree of quality in architectural buildings that is likely to lead to user satisfaction, architectural design relies on integrating user-related information even before generation of building concepts.
BOUCHARD, Carole +2 more
core