Results 121 to 130 of about 21,360,861 (309)

UA30/1/1 Kentucky Building Renovation Sketches [PDF]

, 1974
Drawings created by unknown architect showing a possible addition and renovation to the Kentucky Building which housed the Kentucky Library & Museum.
WKU Planning, Design & Construction
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

UA30/1/1 Western Kentucky State College Map [PDF]

, 1960
Western Kentucky University campus map which includes: Van Meter Hall Gordon Wilson Hall Cherry Hall Training School Faculty House Diddle Dorm Home Economics Building razed 1982 Garrett Conference Center Potter Hall Industrial Arts Building Helm ...
WKU Planning, Design & Construction
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Tasarımda Arte Povera Ethosu ve Örnekleri Üzerine Bir Değerlendirme

PLANARCH - Design and Planning Research
Birçok ülkede siyasal ve toplumsal hareketler farklı dönemlerde olumsuz durumların yaşanmasına sebep olmuş, tüm bu sıkıntılı süreçler yaşamın her alanında farklı etkiler/değişimler/oluşumlar ortaya çıkarmıştır.
Merve Buldaç
doaj   +1 more source

To Design a Designer To Design Designs

, 2008
PUBLISHED This paper reports on the implementation of a new project based design course at first year level of an engineering degree programme. The project, carried out in groups of six, uses the design and construction of a ?Mangonel?, or catapult, as its primary task.
openaire   +1 more source

Towards a Theory of Software Development Expertise

, 2018
Software development includes diverse tasks such as implementing new features, analyzing requirements, and fixing bugs. Being an expert in those tasks requires a certain set of skills, knowledge, and experience.
Anders Ericsson K., Andrew, Curtis Bill, Design, Expert, Garland Ron, Kagdi Huzefa H., Kalliamvakou Eirini, Tourish Dennis   +8 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The effect of interior design on the dynamics of movement of children with learning disabilities within the educational space

Journal of Architecture, Art & Humanistic Science
The child uses movement from the early stages, and expresses his needs, feelings before the ability to speak. So movement is a social means by which an individual deals with his world around him just like language; Movement occurs either by the influence
Prof. Adel Adly Ibrahim, Researcher. Heba Abdel Salam Ibrahim Fayed   +1 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source