Results 131 to 140 of about 15,545,883 (264)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2018 Effective practices for briefing and sales represent a prime concern for design consultants in settling the scope of their work in projects. In order to understand this process, we undertook an inductive thematic analysis of interviews with, and ...
Person, Oscar, Park-Lee, Seungho
core
, 2020 Ce "Lexique du Design" wallon vise un objectif essentiel: fournir un livrable opérationnel aux entrepreneurs et opérateurs technologiques qui soit à même de promouvoir les qualités et valeurs ajoutées d’une démarche innovante nourrie par les ...
Yonder, Cigdem +2 more
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
, 2008 This paper reports on recent developments on an international collaborative industrial design studio project entering its fourth year of existence between three universities in three different countries.
Novoa, Mauricio (R13411)
core
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Modeling the early stages of a user-centered process in architectural design through adaptation of the methodologies of New Product Design [PDF]
, 2009 In order to reach a degree of quality in architectural buildings that is likely to lead to user satisfaction, architectural design relies on integrating user-related information even before generation of building concepts.
BOUCHARD, Carole +2 more
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Revista Brasileira de Engenharia Agrícola e Ambiental, 2013 Para que projetos de silos verticais que envolvam armazenagem de produtos sólidos sejam seguros e confiáveis, é importante que se conheça o maior número de variáveis possíveis, tais como: propriedades de fluxo, geometria do silo e tipo de fluxo desejado.
José P. Lopes Neto +1 more
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
In Relation : Brazilian Indigenous Fashion Design
This work explores ways of de-centring the current mainstream western fashion design practice discourse by investigating the work of contemporary Brazilian indigenous fashion designers. Today, the practices and relationships established by fashion design
Valle-Noronha, Julia
core +1 more source