Results 131 to 140 of about 21,360,861 (309)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
EXPLORATION METHOD OF ROSTER DESIGN DEVELOPMENT WITH METAL WASTE IN TUMANG VILLAGE CEPAGA BOYOLALI [PDF]
, 2019 In Tumang village as a center for copper handicrafts, the problem that arises is the abundant metal waste but has not been used optimally. The aim is to develop a roster design made from metal waste with consideration of aesthetic appearance and ...
Setyawan, S. (Setyawan) +2 more
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Design of a CMOS closed-loop system with applications to bio-impedance measurements [PDF]
, 2010 This paper proposes a method for impedance measurements based on a closed-loop implementation of CMOS circuits. The proposed system has been conceived for alternate current excited systems, performing simultaneously driving and measuring functions ...
Rueda Rueda, Adoración +1 more
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
UA30/1/1 Landscape Work, Classroom Building [PDF]
, 1936 Landscape Work, Classroom Building, PWA KY-1043-R, UA30/1/1 Includes plan with details and sections for area surrounding Cherry Hall and Cedar ...
WKU Planning, Design & Construction
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Moscow Agglomeration: the 1st Stage of the Competition
Проект Байкал, 2012 - Strelka Institute for Media, Architecture and Design
doaj +1 more source
Urban Design of Bristol Waterfront, Lower Thames Street [PDF]
, 2013 Collaboration with the Town of Bristol in the fall of 2013 when students in ARCH 415, Advanced Design Studio – Urban, under the guidance of Professor Ulker Copur, studied the waterfront area along the west side of Thames Street, from State Street south ...
Fall 2013 ARCH 415 Advanced Design Studio – Urban Class, Roger Willaims University +1 more
core +1 more source