Results 81 to 90 of about 7,828,613 (296)

The “who designed the designer?” objection to design arguments [PDF]

open access: yesInternational Journal for Philosophy of Religion, 2013
One of the most commonly-raised objections to the design argument is the so-called “who designed the designer?” objection, which charges that any designer invoked to explain complexity in the universe will feature complexity of its own, and thus require explanation in terms of design.
openaire   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Evaluating variables of patient experience and the correlation with design

open access: yesPatient Experience Journal, 2017
The objective of this paper was to understand the variables of patient experience by analyzing recent and relevant evidence and to identify design solutions within the hospital environment that positively impact those variables.
Dyutima Jha   +2 more
doaj  

Design, Educação e Formação. Uma visão situada e transversal

open access: yesDEDiCA, 2018
A escola é uma identidade na qual o aprender e a reprodução do saber devem consubstanciar uma cultura educacional e formativa indutora da compreensão renovada do quotidiano social e consentânea com a emergência das complexidades do nosso tempo ...
Bartolomeu Paiva
doaj   +1 more source

Design Anthropology in Participatory Design [PDF]

open access: yesInteraction Design & Architecture(s) Journal, 2015
This focus section explores the opportunities of design anthropology in participatory design as an approach to research and design in an increasingly global and digital world. Traditionally, ethnography has been used in Participatory design to research real-life contexts and challenges, and as ways to involve people in defining user-needs and design ...
Smith, Rachel Charlotte   +1 more
openaire   +4 more sources

Mycobacterium tuberculosis sulfurtransferase SseA is activated by its neighboring gene product Rv3284

open access: yesFEBS Letters, EarlyView.
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli   +10 more
wiley   +1 more source

Adaptability of Kitchen Furniture for Elderly People in Terms of Safety

open access: yesDrvna Industrija, 2012
The number of senior citizens is rapidly increasing, which consequently signifi es an increase in the number of people having sight, hearing or memory diffi culties, people with hampered mobility, and people who find it increasingly diffi cult to process
Jasna Hrovatin   +4 more
doaj  

To Design a Designer To Design Designs

open access: yes, 2008
PUBLISHED This paper reports on the implementation of a new project based design course at first year level of an engineering degree programme. The project, carried out in groups of six, uses the design and construction of a ?Mangonel?, or catapult, as its primary task.
openaire   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

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