Results 151 to 160 of about 636,549 (266)

Design and construction of nanoengineered multifunctional microneedles with sustained-release properties for targeted microenvironment remodeling in diabetic bone regeneration. [PDF]

Mater Today Bio
Gong H, Ma S, Wang B, Liu Y, Han X, Wang Y, Sun D, Su Y, Wang J, Zhao J.   +9 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Optimization of architectural design and construction with integrated BIM and PLM methodologies. [PDF]

Sci Rep
Zhang S, Tang Y, Zou Y, Yang H, Chen Y, Liang J.   +5 more
europepmc   +1 more source

Design and construction of a customizable phantom for the characterization of the three-dimensional magnetic resonance imaging geometric distortion. [PDF]

J Appl Clin Med Phys, 2021
Torfeh T, Hammoud R, Paloor S, Arunachalam Y, Aouadi S, Al-Hammadi N.   +5 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Design and Construction of a Portable IoT Station. [PDF]

Sensors (Basel)
Trape MA, Hellany A, Shah SKH, Rizk J, Nagrial M, Famakinwa T.   +5 more
europepmc   +1 more source

Intelligent Design of Construction Materials: A Comparative Study of AI Approaches for Predicting the Strength of Concrete with Blast Furnace Slag. [PDF]

Materials (Basel), 2022
Wu X, Zhu F, Zhou M, Sabri MMS, Huang J.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Design and construction of a low-cost, low-input Open Top Chamber field warming setup to assess aboveground plant response to global warming. [PDF]

Front Plant Sci
Hauser J, Kooijman PC, Paddon END, Verhoeven A, Kalisvaart J, Meesters AN, Snoek BL, van Zanten M.   +7 more
europepmc   +1 more source

Design and Construction of a Chamber Enabling the Observation of Living Cells in the Field of a Constant Magnetic Force. [PDF]

Cells, 2021
Dziob D, Ramian J, Ramian J, Lisowski B, Laska J.   +4 more
europepmc   +1 more source