Results 111 to 120 of about 5,009,941 (320)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Design and deformation pattern simulation of deep excavation support structures

Frontiers in Earth Science
This study delves into the design and deformation patterns of support structures in urban deep excavation projects, aiming to optimize the design of these structures to ensure their safety and stability.
Shijiang Li, Fengcun Wang, Yi Le, Qiaoyun Que, Yu Su, Huiting Lin   +5 more
doaj   +1 more source

Design and pattern development of the shape of a tense structure

Revista de Arquitectura (Bogotá), 2018
ResumenCon el objetivo de crear una metodología de adecuaciones geométricas de las superficies mínimas, se planteó un método que parte de la sistematización de pasos realizada en un programa virtual, para luego formar modelos físicos a escala y tamaño ...
Carlos César Morales-Guzmán
doaj   +1 more source

Design Patterns Past and Future [PDF]

InSITE Conference, 2011
A very important part of the software development process is service or component internal design and implementation. Design Patterns (Gamma et al., 1995) provide list of the common patterns used in the object-oriented software design process. The primary goal of the Design Patterns is to reuse good practice in the design of new developed components or
openaire   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source

Using pattern languages in participatory design [PDF]

, 2002
In this paper, we examine the contribution that pattern languages could make to user participation in the design of interactive systems, and we report on our experiences of using pattern languages in this way.
Allgar, E., Dearden, Andy, Finlay, J., McManus, B.   +3 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Indigenous peoples and artificial intelligence: A systematic review and future directions

Big Data & Society
This systematic literature review addresses the intersection of two rapidly evolving areas of knowledge and practice: Indigenous Knowledge Systems (IKS) and artificial intelligence (AI).
Maneesha Perera, Rajith Vidanaarachchi, Sangeetha Chandrashekeran, Melissa Kennedy, Brendan Kennedy, Saman Halgamuge   +5 more
doaj   +1 more source

Pattern Design to Optimize Transformation and Innovation Packages in Medical Education

آموزش پزشکی, 2022
Background and Objective: The purpose of this study aims to identify and explain the dimensions and components of the optimal implementation of transformation and innovation packages in medical education, which is an exceptional opportunity for educators
RAZIEH ghorbandoost, hamidreza arasteh, hosein abasian, hasanreza zinababdi, aseman shafi abadi   +4 more
doaj