Results 191 to 200 of about 4,753,099 (348)

COnCEPT - Developing Intelligent Information Systems to Support Colloborative Working Across Design Teams

open access: gold, 2014
Aggelos Liapis   +9 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

How the Lack of Chitosan Characterization Precludes Implementation of the Safe-by-Design Concept. [PDF]

open access: yesFront Bioeng Biotechnol, 2020
Marques C   +4 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Design concept and phase transformation study of advanced bainitic-austenitic medium-Mn steel. [PDF]

open access: yesSci Rep
Wojtacha A   +6 more
europepmc   +1 more source

Independent Tailoring of Dose and Drug Release via a Modularized Product Design Concept for Mass Customization. [PDF]

open access: yesPharmaceutics, 2020
Govender R   +5 more
europepmc   +1 more source

Towards Operator Empowerment in Assembly Lines with Human-Centered Design: A Concept with Application in the Automotive Industry

open access: diamond
Johannes Zysk   +7 more
openalex   +1 more source

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