Results 191 to 200 of about 5,644,068 (291)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Intelligent Evaluation Method for Design Education and Comparison Research between visualizing Heat-Maps of Class Activation and Eye-Movement. [PDF]
J Eye Mov ResJiayi J, Tianjiao Z, Junyu Y, Qian W.
europepmc +1 more source
Design of Learning Media in Mixed Reality for Lao Education
, 2020 Kalaphath Kounlaxay, Soo Kyun Kim
openalex +1 more source
FEBS Open Bio, EarlyView.Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
Design and Evaluation of Sensor Module for Portable Programmable Logic Controller (PLC) Kit for Automated Control Education [PDF]
, 2016 Sheng‐Jen Hsieh
openalex +1 more source
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Research on the Design of Talent Training Mode Based on qThe Ordered Classq for Certain Majors in Vocational Education [PDF]
, 2017 Huajuan Lin, Wenguan Huang, Xiao Hu
openalex +1 more source