Results 171 to 180 of about 18,580,692 (312)

Design is not for the weak: on the use in design education

Arcos Design, 2022
openaire   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Embedding indigenous knowledge : seeking new design opportunities at the edge of the cultural interface : an Australian education case study

, 2011
This paper explores the development of innovative curriculum pathways for highlighting the opportunities for designers in projects focusing on improved emotionally supportive and new practical outcomes for indigenous and non-indigenous communities ...
Alexander, Sasha (R7191)
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Designing for Our Future Selves: A Case Study in Age-Inclusive Design Education Through a Reflective Workshop

Transformative Social Impact
As the global population ages, the design field faces an urgent imperative to confront ageism and foster more inclusive practices. Yet age-inclusive design remains underrepresented in both education and professional settings—often treated as a niche ...
Kimberly Mitchell
doaj   +1 more source

Development and evaluation of a desktop VR serious game for color composition learning in basic design education. [PDF]

PLoS One
Sun J, Zhang J, Chen W, Fan J, Hao F, Lai H.   +5 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Integrating Imagination and Design Thinking: Pedagogical Approaches for Postgraduate Creativity

International Journal of Arts Architecture & Design
Examining the function and possible effects of the "Imaginative Design Thinking" courses created for postgraduate Master of Design (M.Des) students, this paper places its inception within the changing context of higher education.
Rahat Varma
doaj   +1 more source

Research on the emerging technological intervention models in design education from a strategic perspective of global design education institutions. [PDF]

Sci Rep
Chen F, Lin Z, Li X.
europepmc   +1 more source

Research on the Integrated Development of Local Art Design and Art Design Education in the New Media Environment.

J Environ Public Health, 2022
Wang Z, Liu B.
europepmc   +1 more source