Results 151 to 160 of about 4,260,477 (269)
Nudging: How human behavior is affected by design
, 2016 A statement in this article expresses that there is no such thing as neutral design, and that the way something is designed will affect the person using it in one way or another.
Hunnes, Mari Gloppen
core
Teachers’ Scaffolding Strategies in Relation to Enacted Verbal Reasoning in the Design Process
Learning to reason in the design process is enclosed in the process of learning to design. Hence, in this study, we explore teacher-student interactions with the aim of describing teachers’ support strategies in relation to enacted reasoning in the ...
Gullberg, Annica +2 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Tutorial: Software Design Strategies.--2nd. ed
, 1981 A tutorial text attempting to clarify and focus on aspects of software design that have direct effect on the structure of the final program. Several major design strategies are developed and compared, including: traditional forms of functional ...
G. Bergland, R. Gordon
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Valuing health and wellbeing using discrete choice experiment: exploring feasibility, design effect and international preference similarity. [PDF]
Eur J Health EconWang H +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Big Data Analysis, Design, Effect Fabrication, and Properties Analysis of SiO2/Cr/SiO2 Colored Solar Selective Absorbers with High PTCE and Chromaticity for Building Applications. [PDF]
Materials (Basel)Lai FD, Lai YT, Chen CS.
europepmc +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source