Effects of Different Staircase Design Factors on Evacuation of Children from Kindergarten Buildings Analyzed via Agent-Based Simulation. [PDF]
Zhou J, Jia X, Jia J.
europepmc +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Design Factors; Tools for Design Thinking
As more and more people find themselves confronted with design issues - in the roles of planners,developers, and producers - tools which can assist communication across different domains of expertise facilitating participation in design processes and supporting evaluation as well as documentation, are required.
openaire +1 more source
Design Research and Public Policy: Current Practice Working to Intersect with Government
Design research is an academic and practical field of study that seeks to explore the ways in which design in any discipline area is produced, understood, and used.
Parliamentary Design and Innovation Group, All Party
core
The Effect of BEOL Design Factors on the Thermal Reliability of Flip-Chip Chip-Scale Packaging. [PDF]
Li D +8 more
europepmc +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Beyond violations : human factors in maintenance failures
Human factors are recognised as influencing the performance of workgroups in industrial operations. Surveys and interventions in high-risk industries, notably commercial aviation and power generation, have highlighted the practical implications of a ...
Antonovsky, Ari +1 more
core
Augmented reality for endoscopic transsphenoidal surgery: evaluating design factors with neurosurgeons. [PDF]
Higa J +6 more
europepmc +1 more source
Univariate associations between housing, management, and facility design factors and the prevalence of lameness lesions in fourteen small-scale dairy farms in Northeastern Algeria. [PDF]
Dendani-Chadi Z +5 more
europepmc +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source

