Results 191 to 200 of about 20,506,281 (310)

A hierarchical Bayesian approach to robust parameter design. [PDF]

The goal of robust parameter design experiments is to identify significant location and dispersion factors that can be used to set the mean response at the target level and to decrease the sensitivity of the response to uncontrolled noise factors.
Goos, Peter, Vandebroek, Martina, Goegebeur, Yuri   +2 more
core  

A statistical analysis of the effect of design factors of the cylindrical battery module on the thermal behavior by C-rate. [PDF]

Heliyon
Park S, Lee H, Park C, Kim CW.
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Hierarchical nested honeycomb-based energy absorbers: design factors and tailorable mechanical properties. [PDF]

Interface Focus
Ghimire A, Hsu CH, Lin CC, Chen PY.
europepmc   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

The Impact of Design Factors on User Behavior in a Virtual Hospital Room to Explore Fall Prevention Strategies. [PDF]

HERD
Seddighi N, Chen YC, Merryweather AS, Foreman KB, Kuntz A, Battaglia E, Zhang H, Taylor E, Wong B, Fino PC.   +9 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Revisiting Urban Street Planning and Design Factors to Promote Walking as a Physical Activity for Middle-Class Individuals with Metabolic Syndrome in Cairo, Egypt. [PDF]

Int J Environ Res Public Health
Abusaada H, Elshater A.
europepmc   +1 more source

Design factors for determining the radula shape of Euhadra Peliomphala. [PDF]

Sci Rep, 2019
Miura S, Saito R, Parque V, Miyashita T.
europepmc   +1 more source