Results 51 to 60 of about 19,879 (265)

Práticas e desafios na preparação da produção em projetos de novos produtos de higiene pessoal Practices and barriers in the manufacturing preparation of new products at a personal hygiene product enterprise

open access: yesProduction, 2008
A literatura sobre o processo de desenvolvimento de produtos (PDP) dedica pouca atenção à etapa de preparação dos meios de manufatura. Em certos produtos, porém, o diferencial tecnológico está justamente no processo de fabricação.
Felipe Botta Tarallo   +1 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Structure of the product design and assessment of its complexity level from the point of labor intensity of manufacturing and operational efficiency

open access: yesВесці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук
Based on the fact that the complexity of the product design affects the labor intensity of its manufacture and the efficiency of operation, the concept of product complexity is formulated by determining the number of levels of the design structure. It is
B. M. Bazrov   +2 more
doaj   +1 more source

Simulation analysis of performances and yield rates on a lens module

open access: yesAdvances in Mechanical Engineering, 2017
A simulation platform is developed to analyze the tolerance ability of designed lens in the opto-mechanical system. The major task of lens designer is to find out the optimal parameters to meet the specification requirement.
Cheng-Mu Tsai, Kuan-Chieh Huang
doaj   +1 more source

Study on Adopting Measuring Technology(CAT) for Producing Automotive Closure Parts

open access: yesInternational Journal of Automotive Engineering, 2012
This paper descries the measuring technology, so-called CAT (Computer Aided Testing) technology which is the most important to design and manufacture of automotive closure parts, such as doors, exhausts systems and its production equipment, to give ...
Kazuo Muto   +2 more
doaj   +1 more source

SUBASSEMBLIES OF THE PARACHUTE CONTAINER WITH IMPROVED GEOMETRY BASED ON DIGITAL SOLUTIONS [PDF]

open access: yesAnnals of the University of Oradea: Fascicle of Textiles, Leatherwork, 2022
The recovery system used in the aeronautic field have, as a main element, the whole set of parachutes, that represents a very complex system for which a thorough knowledge of the performance characteristics of the component materials is required, as well
JOMIR Mihaela, SALISTEAN Adrian
doaj  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Modular architecture principles – MAPs: a key factor in the development of sustainable open architecture products

open access: yesInternational Journal of Sustainable Engineering, 2020
Modularity is one of the most useful tools employed in the product development process. Regarding functionality, the use of modules is common to generate flexible platforms to manufacture products and product families that require functional variations ...
Jaime Alberto Mesa   +2 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy