Results 91 to 100 of about 10,948,845 (303)
Real options analysis for adaptable buildings: a cost and carbon analysis
Environmental Research: Infrastructure and SustainabilityThere is increasing interest in adaptable building design as spatial needs, market conditions, and performance expectations evolve over time. Uncertainty in future demand requires designers to assess not only the financial implications of expansion ...
Doreen Steven Mlote +4 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida +11 more
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Time and futures. Analysis of time-needs in futures research [PDF]
This paper discusses temporalities in futures research in terms of a novel notion of time-need. It is argued that this notion contributes to the theoretical and critical discussion about time in futures research.
Virmajoki, Veli, Laakkonen, Mika-Petri
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Journal of Innovation Management, 2018 In this conceptual paper, we review the literature spanning the Strategic Planning, Foresight and Design disciplines with the emphasis placed on how innovation stakeholders may engage with the future in order to explore the challenges to decision-making ...
Joern Henning Buehring, Jeanne Liedtka
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Frontiers in Sustainable CitiesFutures thinking is a crucial skill for organisations navigating volatile, uncertain, complex, and ambiguous environments. Nonetheless, some researchers and practitioners argue that the insights futures thinking can yield appear obvious, trivial, or ...
Maria Vitaller del Olmo +4 more
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FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
, 2018 A multi-Disciplinary View at Contingent Futures – Beyond the Placative Dualism of Design versus Disaster.Welche Rolle spielt Design in gesellschaftlichen Transformationsprozessen?
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Futures thinking becomes a priority for all globalized societies
Discover Global SocietyThis essay provides a concise impression of the many contemporary attempts to revitalize futures thinking. Futures thinking—in the sense of a systematic anticipatory approach based on sound scientific expertise and backed by socio-philosophical reasoning
Roland Benedikter
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FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source