Results 121 to 130 of about 14,534,189 (338)
PC-based Multiple Information System Interface (PC/MISI) design plan [PDF]
The general design plan for the implementation of a common user interface to multiple remote information systems within a microcomputer-based environment is presented.
Dominick, Wayne D., Hall, Philip P.
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
This design note presents a study of the Procedures and Performance Program (PPP) effectiveness. The intent of the study is to determine manpower time savings and the improvements in job performance gained through PPP automated techniques. The discussion
Arbet, J. D., Benbow, R. L.
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Acoustic evaluation of a novel swept-rotor fan [PDF]
Inlet noise and aerodynamic performance are presented for a high tip speed fan designed with rotor blade leading edge sweep that gives a subsonic component of inlet Mach number normal to the edge at all radii. The intent of the design was to minimize the
Lucas, J. G. +2 more
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Study of blade aspect ratio on a compressor front stage aerodynamic and mechanical design report [PDF]
A single stage compressor was designed with the intent of demonstrating that, for a tip speed and hub-tip ratio typical of an advanced core compressor front stage, the use of low aspect ratio can permit high levels of blade loading to be achieved at an ...
Burger, G. D., Lee, D., Snow, D. W.
core +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Data Management Systems (DMS): Complex data types study. Volume 1: Appendices A-B. Volume 2: Appendices C1-C5. Volume 3: Appendices D1-D3 and E [PDF]
Two categories were chosen for study: the issue of using a preprocessor on Ada code of Application Programs which would interface with the Run-Time Object Data Base Standard Services (RODB STSV), the intent was to catch and correct any mis-registration ...
Davari, Sadegh +3 more
core +1 more source