Results 211 to 220 of about 14,534,189 (338)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Sense of Belonging, Burnout, and Work Intentions Among US Physicians.

JAMA Netw Open
Carlasare LE, Shah P, Turzi A, Nankivil N, Fogg J, Rotenstein LS.   +5 more
europepmc   +1 more source

High dietary fiber is associated with improved outcomes in patients with melanoma and sarcoma treated with immunotherapy regardless of gut microbiome dysbiosis and social vulnerability. [PDF]

Cancer
Fields BC, Traweek RS, Jiang K, Witt RG, Damania A, Chiang YJ, Ajami N, Nassif-Haddad E, Keung EZ, Chelvanambi M, Zhang X, Peterson CB, Wargo JA, Daniel CR, Roland CL, Holder AM.   +15 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Does Intent Regarding Abusive Supervision Really Matter? The Moderating Effect of Performance-Promotion and Injury-Initiation Attributions Between Abusive Supervision and Emotional Exhaustion. [PDF]

Behav Sci (Basel)
Liu T, Kilroy S, Zhang Y.
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Does the Intent Match the Output: Aligning Development Goals With Training Load in Youth Basketball. [PDF]

Eur J Sport Sci
Lever JR, Duffield R, Murray A, Bill HA, Bartlett JD, Fullagar HHK.   +5 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Understanding User Intent in Code-Mixed Sexual and Reproductive Health Queries in Urban India: Hierarchical Classification Approach Using Large Language Models.

J Med Internet Res
Dey SK, S M, Thapa A, Shah M, Mehta Z, Kapile SK, Divate T, Jalota S, Ismail A.   +8 more
europepmc   +1 more source

AI based decision-making system for tooling design of aircraft product assembly with developed knowledge retrieval algorithm. [PDF]

Sci Rep
Miah MH, Gupta SK, Yali L, Alsekait DM, Alzu'bi S, Nabil A, Chowdhury HR, Kanon M.   +7 more
europepmc   +1 more source