Results 71 to 80 of about 13,948,543 (335)
Background Producing graduates for a breadth of sectors is a priority for veterinary science programs. Undergraduate career intentions represent de-facto ‘outcome’ measures of admissions policy and curricula design, as intentions are strong predictors of
A. M. Feakes +7 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Developing a current capability design for manufacture framework in the aerospace industry [PDF]
Organised by: Cranfield UniversityDuring progressive product design and development in the aerospace industry, a lack of effective communication between the sequential functions of design, manufacturing and assembly often causes delays and setbacks ...
Shehab, Essam +3 more
core
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Design of intentional backdoors in sequential models
Recent work has demonstrated robust mechanisms by which attacks can be orchestrated on machine learning models. In contrast to adversarial examples, backdoor or trojan attacks embed surgically modified samples with targeted labels in the model training process to cause the targeted model to learn to misclassify chosen samples in the presence of ...
Zhaoyuan Yang +3 more
openaire +2 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Tin cans, brass, cord, wood, plastic milk bottle, electrical fittings, wood Tin cans and milk bottles, to name just two examples from a countless number of things, are excellent specimens of design.
Rubenis, Niklavs
core
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Building Information Graphs (BIGs): remodeling building information for learning and applications
Despite significant advances in Building Information Modeling (BIM) and increased adoption, numerous challenges remain. Discipline-specific BIM software tools with file storage have unresolved interoperability issues and do not capture or express ...
Zijian Wang, Rafael Sacks
doaj +1 more source
Design intent tool: User guide [PDF]
This database tool provides a structured approach to recording design decisions that impact a facility's design intent in areas such as energy efficiency.Owners and de signers alike can plan, monitor and verify that a facility's design intent is being ...
Stum, Karl +9 more
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