Results 91 to 100 of about 23,644,290 (315)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

From Fragment to One Piece: A Review on AI-Driven Graphic Design

open access: yesJournal of Imaging
This survey offers a comprehensive overview of advancements in Artificial Intelligence in Graphic Design (AIGD), with a focus on the integration of AI techniques to enhance design interpretation and creative processes.
Xingxing Zou, Wen Zhang, Nanxuan Zhao
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

DESIGN OF LOW-POWER ELECTRONIC SYSTEMS USING UPF POWER INTENT SPECIFICATION TECHNOLOGY

open access: yesInformatika, 2016
In this review paper, the problem of the design of energy-efficient electronic systems is considered. Different energy-saving methods are presented. The necessity of additional tools of formal behavioral description of the power subsystem is explained ...
A. S. Shashkov
doaj  

A review of the design intent concept in the context of CAD model quality metrics

open access: yes, 2014
From the perspective of Computer Aided Design (CAD), Design Intent is a term commonly defined as a model’s anticipated behavior once it undergoes alteration (ex.
Jeffrey M. Otey, M. Contero
semanticscholar   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Prompt Design Workflow Based on User Contextual Language for Generative Artificial Intelligence Conceptual Design: A Case Study of Agricultural Tools for Elderly Farmers

open access: yesEngineering Proceedings
In early-stage product ideation, generative AI has emerged as a design support tool, yet most prompts still rely on designers’ subjective intent with limited grounding in user context. Therefore, we developed a user-centered prompting method, introducing
Hung-Hsiang Wang, Yueh-Lin Huang
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Intent-to-treat results.

open access: yes, 2019
Intent-to-treat results.
Ronelle Burger (4638334)   +2 more
core   +1 more source

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