Results 121 to 130 of about 9,794,765 (303)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Interconnect design methods for memory design [PDF]

open access: yesASP-DAC 2004: Asia and South Pacific Design Automation Conference 2004 (IEEE Cat. No.04EX753), 2004
Chanseok Hwang, Massoud Pedram
openaire   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Research on the intelligent generation of the spatial form of the island city historic district Based on parameterization: taking Macau Taipa Village as an example

open access: yesJournal of Asian Architecture and Building Engineering
In this paper, Macau Taipa Village, a historical district in an island-type city, is the research focus, and a parametric design-based method for designing historical districts is proposed.
Yile Chen, Liang Zheng, Lina Yan
doaj   +1 more source

Mechanical Performance of Joints with Bearing Plates in Concrete-Filled Steel Tubular Arch-Supporting Column-Prestressed Steel Reinforced Concrete Beam Structures: Numerical Simulation and Design Methods

open access: yesBuildings
Research on the configuration and mechanical performance of arch-column-tie beam joints, which combine features of arch-tie beam joints and tubular joints, remains limited, particularly for long-span structures subjected to heavy loads at high building ...
Chongyang Li   +4 more
doaj   +1 more source

Design of transonic compressor cascades using hodograph method [PDF]

open access: yes
The use of the Hodograph Method in the design of a transonic compressor cascade is discussed. The design of the flow mode in the transonic compressor cascade must be as follows: the flow in the nozzle part should be uniform and smooth; the location of ...
Chen, Zuoyi, Guo, Jingrong
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Design Approach for Composite Pavement Structure Incorporating Reflective Crack Considerations

open access: yesApplied Sciences
The current design methods employed for composite pavement structures predominantly rely on cement concrete slabs, which unfortunately lack established design standards and associated control indicators for determining the appropriate thickness of the ...
Naren Fang   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy