Results 111 to 120 of about 9,794,765 (303)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Aircraft cabin lighting design method based on DIALux

open access: yesXibei Gongye Daxue Xuebao
Lighting in aircraft cabin is an important part of the aircraft interior lighting system. A reasonable cabin lighting design can improve the quality of flight services and enhance passenger satisfaction and comfort.
FU Jinchi   +3 more
doaj   +1 more source

A decomposition-based design optimization method with applications [PDF]

open access: yes
A two-level design optimization metholology is described. A progress report of its application to Printed Wiring Board (PWB) assembly examples is given.
Azarm, Shapour   +3 more
core   +1 more source

Optimal control theory : a method for the design of wind instruments [PDF]

open access: yes, 2010
It has been asserted previously by the author that optimal control theory can be a valuable framework for theoretical studies about the shape that a wind instrument should have in order to satisfy some optimization criterion, inside a fairly general ...
Vey, Georges Le
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Design process of the Memorial Cathedral for World Peace (1954), Hiroshima, by Togo Murano (Part 4): Formal manipulations observed in the process of working design and construction instruction of the cathedral (1948–1954)

open access: yesJapan Architectural Review
Following schematic design in November 1948, the design effort continued through working design (detailed design prepared for construction work), which was completed in June 1950, and subsequent detailed construction instruction design.
Yoshito Tomioka, Chikako Tabata
doaj   +1 more source

Model-based Optimization of Compressive Antennas for High-Sensing-Capacity Applications [PDF]

open access: yes, 2015
This paper presents a novel, model-based compressive antenna design method for high sensing capacity imaging applications. Given a set of design constraints, the method maximizes the sensing capacity of the compressive antenna by varying the constitutive
Martinez-Lorenzo, Jose Angel   +1 more
core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Structural Optimization of Scarfing Machine with Acceleration Profile and Multi-Objective Genetic Algorithm Approach

open access: yesMachines
Scarfing is a type of flame treatment used to improve the quality of metal generated during steelmaking. It employs the principles of gas cutting to remove impurities and defects.
Sangbin Lee   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy