Results 181 to 190 of about 3,978,056 (320)

Finalisation of experiment of experiment design

Finalisation of experiment of experiment ...
openaire   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Design and experiment of a comb-and-scrape Idesia Polycarpa Maxim threshing device. [PDF]

Sci Rep
Yang G, Wu D, Xu W, Tang Y.
europepmc   +1 more source

Design of experiments assisted the development of inclusion complexes of ramipril using hydrophilic carriers for enhancement of solubility and dissolution rate

, 2023
Azeez Mohammad, Sumer Singh, Suryakanta Swain, Rabinarayan Parhi   +3 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Optimized design and experiment of a controllable rotary tube strip fertilizer spreader for hilly mountainous terrain. [PDF]

Sci Rep
Dun G, Gao S, Ji X, Sun H, Wei Y, Sheng Q, Zhang C, Ma C, Li X, Wang L, Yu Z, Li H, Ma C.   +12 more
europepmc   +1 more source

Design of a Physical Interactive Board game for Traditional Culture Popularization Based on Eye Tracking Experiment [PDF]

Juan Wang
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Optimization of In Vitro Transcription by Design of Experiment to Achieve High Self-Amplifying RNA Integrity. [PDF]

Vaccines (Basel)
Hu C, Wang H, Liu G, Li K, Zhang X, Song L, Gao F, Wu X, Wang Q, Liu M, Liu J, Fu Z, Ma X, Xu M, Mao Q, Liang Z, He Q.   +16 more
europepmc   +1 more source

Design of Experiment for Optimizing Microencapsulation by the Solvent Evaporation Technique. [PDF]

Polymers (Basel), 2023
Loureiro MV, Aguiar A, Santos RGD, Bordado JC, Pinho I, Marques AC.   +5 more
europepmc   +1 more source