Results 201 to 210 of about 3,978,056 (320)

Experimental Investigation of Edm Die Sinking Process Parameters on Aluminium Alloy 5083 Using Design of Experiment

, 2017
Wahaizad Safiei, Muhamad Ridzuan Radin Muhamad Amin   +1 more
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Design and experiment of spiral conveying pipe in pneumatic centralized fertilizer discharge system. [PDF]

PLoS One
Zhang L, Yuan W, Feng Y, Jin C, Liu G, Xie S.   +5 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Design and experiment of key components for self-propelled harvester for Chinese cabbage. [PDF]

Sci Rep
Yu Y, Qi J, Li Y, Xie F, Song J, Bai Y.
europepmc   +1 more source

Design and Experiment Investigation on Soft Grippers with Modular Variable Stiffness Structure. [PDF]

Micromachines (Basel), 2023
Zhao P, Xiong C, Gao Z, Liu X, Zeng Y.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Design and Experiment of Tea Fresh Leaf Sorting Equipment Under Double Negative Pressure Airflow Field Based on CFD-RSM Coupling Optimization. [PDF]

Food Sci Nutr
Zhang X, Wang R.
europepmc   +1 more source

Experiments, conceptual design, preliminary cost estimates and schedules for an underground research facility

, 1981
G. Korbin, H.A. Wollenberg, Clark R. Wilson, B. Strisower, T. Chan, D.E. Wedge   +5 more
openalex   +2 more sources

Implications of an Iterative Design Experiment in Transcendental and Polynomial Functions Within a Flipped Classroom

, 2020
Aaron Boyd Harris
openalex   +1 more source