Results 141 to 150 of about 4,561,954 (333)
ON THE BOOTSTRAP METHOD OF ESTIMATION OF RESPONSE SURFACE FUNCTION
Acta Universitatis Lodziensis. Folia Oeconomica, 2014 Nowadays, in many fields of science it is necessary to carry out miscellaneous analyses using classical statistical methods, which usually have correct assumptions.
Małgorzata Szerszunowicz
doaj
Context and Interpretation in Laboratory Experiments: The Case of Reciprocity [PDF]
The existing literature acknowledges that a mismatch between the experimenter's and the subjects' models of an experimental task can adversely affect the interpretation of data from laboratory experiments.
Birendra K. Rai +2 more
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Curriculum Design and Practice of Ideological and Political Education in Physical Chemistry Experiment for New Energy Materials and Devices Major—A Case Study of “Preparation and Properties of Ferric Hydroxide Colloid” [PDF]
锐 童
openalex +1 more source
Urban Design, Public Spaces, and Social Cohesion: Evidence from a Virtual Reality Experiment
, 2020 Jimena Llopis Abella +3 more
openalex +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Surface roughness analysis in milling machining using design of experiment [PDF]
, 2020 Mehdi Moayyedian +4 more
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source