Results 201 to 210 of about 4,561,954 (333)

Design of Experiments for Dynamic Test Runs in Solvent-Based CO₂ Capture Pilot Plants. [PDF]

Ind Eng Chem Res
Chinen AS, Morgan JC, Bhattacharyya D, Omell B, Matuszewski M.   +4 more
europepmc   +1 more source

Design of simulation experiments [PDF]

Kleijnen, J.P.C.
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Design of Experiments Approach for Efficient Heavy Metals Stabilization Using Metakaolin-Based Geopolymers. [PDF]

Molecules
Russo RE, Santoni E, Fattobene M, Giovini M, Genua F, Leonelli C, Lancellotti I, Herrero A, Berrettoni M.   +8 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

MINE: a new way to design genetics experiments for discovery. [PDF]

Brief Bioinform
Torres I, Zhang S, Bouffier A, Skaro M, Wu Y, Stupp L, Arnold J, Chung YA, Schuttler HB.   +8 more
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Optimization of a Dissolvable Lipid Nanoparticle Microneedle Formulation for mRNA Delivery Using Design of Experiments. [PDF]

ACS Appl Mater Interfaces
Zhao Y, Zhang Q, Hu T, Kuwentrai C, Zhang Y, Huang JD, Kuang Y, Xu C.   +7 more
europepmc   +1 more source

Privacy Preserving Adaptive Experiment Design [PDF]

Jiachun Li, David Simchi‐Levi, Kaining Shi   +2 more
openalex   +1 more source

Integrated design, execution, and analysis of arrayed and pooled CRISPR genome editing experiments [PDF]

, 2017
Matthew C. Canver, Maximilian Haeussler, Daniel E. Bauer, Stuart H. Orkin, Neville E. Sanjana, Ophir Shalem, Guo‐Cheng Yuan, Feng Zhang, Jean‐Paul Concordet, Luca Pinello   +9 more
openalex   +1 more source