Experimental Study on Mechanical Properties and Mix Design Optimization of Nano-SiO<sub>2</sub>-Double-Doped Fiber High-Strength Concrete. [PDF]
Zhu Y +5 more
europepmc +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
An adaptive multi-scale kriging framework with committee-based infill for engineering design optimization. [PDF]
Xie H, Zhong Q, Zeng W.
europepmc +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Quality by design optimization of microemulsions for topical delivery of <i>Passiflora setacea</i> seed oil. [PDF]
Pereira DT +11 more
europepmc +1 more source
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Green spectrofluorimetric determination of clemastine using nitrogen and phosphorus Co-doped carbon quantum dots with face-centered design optimization and sustainability assessment. [PDF]
Almrasy AA, Al Kamaly O, Sayedahmed M.
europepmc +1 more source
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Carbon fiber reinforced composite material layup design optimization method and its application in automobile battery box. [PDF]
Lu D +6 more
europepmc +1 more source

