Results 71 to 80 of about 4,770,902 (292)

MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou, Regina Kubica, Karen Fischhuber, Jasmin Beygo, Madlen Reschke, Petra Ritter‐Sovinz, Eva Biewald, Petra Ketteler, Dietmar Lohmann, Deniz Kanber   +9 more
wiley   +1 more source

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

Issues Affecting Security Design Pattern Engineering [PDF]

, 2013
Security Design Patterns present the tried and tested design decisions made by security engineers within a well documented format. Patterns allow for complex security concepts, and mechanisms, to be expressed such that non domain experts can make use of ...
de Muijnck-Hughes, Jan, Duncan, Ishbel
core  

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

AIR PASSENGER SUPPORT SYSTEM USING LOCATION MONITORING TECHNOLOGIES

Надежность и качество сложных систем
Background. The article presents a system for monitoring the location of air passengers in the airport building, providing a service for notifying those who are late for boarding, as well as providing an effective way to quickly get to the boarding ...
D.V. Egzhov, L.A. Nadeykina, P.O. Tereshko   +2 more
doaj   +1 more source

Analyzing eye movement patterns to improve map design [PDF]

, 2010
Recently, the use of eye tracking systems has been introduced in the field of cartography and GIS to support the evaluation of the quality of maps towards the user.
De Maeyer, Philippe, Fack, Veerle, Ooms, Kristien   +2 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Method for Building Trustworthy Hybrid Performance Models for Cyber-Physical Systems of Systems

IEEE Access
The increasing dynamism and interconnectivity of Cyber-Physical Systems of Systems (CPSoS) emphasize the need for advanced performance modeling approaches.
Mahtab Modaber, Martijn Hendriks, Marc Geilen, Twan Basten, Jeroen Voeten   +4 more
doaj   +1 more source

Test Driven Development: Advancing Knowledge by Conjecture and Confirmation

Future Internet, 2011
Test Driven Development (TDD) is a critical agile software development practice that supports innovation in short development cycles. However, TDD is one of the most challenging agile practices to adopt because it requires changes to work practices and ...
Manfred Lange, Ramesh Lal, David Parsons
doaj   +1 more source