Results 51 to 60 of about 1,250,700 (267)

Packing Oblique 3D Objects

open access: yesMathematics, 2020
Packing irregular 3D objects in a cuboid of minimum volume is considered. Each object is composed of a number of convex shapes, such as oblique and right circular cylinders, cones and truncated cones.
Alexander Pankratov   +2 more
doaj   +1 more source

Sonet Network Design Problems [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2009
This paper presents a new method and a constraint-based objective function to solve two problems related to the design of optical telecommunication networks, namely the Synchronous Optical Network Ring Assignment Problem (SRAP) and the Intra-ring ...
Marie Pelleau   +2 more
doaj   +1 more source

The influence of design on the sollution of waterbody pollution problems

open access: yesАрхитектон, 2023
The article discusses the potential of design for addressing waterbody pollution, one of the most pressing problems of modern urban spaces. A review of domestic and international developments in the area of eco-design shows that they focus on improved ...
Pospelova Anastasia S.   +2 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Design thinking in entrepreneurship education: Understanding framing and placements of problems

open access: yesActa Commercii, 2020
Orientation: Design thinking presented an alternative lens for entrepreneurship education. Research purpose: The purpose of this article was to illustrate (with a framework) the benefits of encouraging a design-based mindset when exploring problem ...
Thea J. Tselepis, Carol A. Lavelle
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Influence of ion implantation and photon annealing regimes on the parameters of implanted n-GaAs:Si layers

open access: yesТехнологія та конструювання в електронній апаратурі, 2005
The paper presents the results of studies on the influence of ion implantation regimes and pulsed incoherent photon annealing on the parameters of Si-implanted n-GaAs layers grown on semi-insulating GaAs substrates.
A. Yu. Bonchyk   +3 more
doaj  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Determination of thermal-physical characteristics of thermal materials at high temperatures

open access: yesАвіаційно-космічна техніка та технологія
This study presents an experimental–numerical method for determining the thermal conductivity and heat capacity of thermal insulation materials (TIM) at elevated temperatures.
Dmytro Borovyk   +5 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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